CAS 320367-13-3|Lixisenatide

Introduction：Basic information about CAS 320367-13-3|Lixisenatide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Lixisenatide BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Lixisenatide
CAS Number	320367-13-3	Molecular Weight	4858.49000
Density	/	Boiling Point	/
Molecular Formula	C₂₁₅H₃₄₇N₆₁O₆₅S	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	lixisenatide
Synonym	More Synonyms

Lixisenatide BiologicalActivity

Description	Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2.
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Glucagon ReceptorResearch Areas >>Metabolic DiseasePeptides
Target	GLP-1 receptor[1][2].
References	[1]. Ahrén B et al. Postprandial Glucagon Reductions Correlate to Reductions in Postprandial Glucose and Glycated Hemoglobin with Lixisenatide Treatment in Type 2 Diabetes Mellitus: A Post Hoc Analysis. Diabetes Ther. 2016 Jun 18 [2]. Lorenz M, et al. Effects of lixisenatide once daily on gastric emptying in type 2 diabetes--relationship to postprandial glycemia. Regul Pept. 2013 Aug 10;185:1-8.

Chemical & Physical Properties

Molecular Formula	C₂₁₅H₃₄₇N₆₁O₆₅S
Molecular Weight	4858.49000
Exact Mass	4855.54000
PSA	2085.46000
LogP	2.13170
InChIKey	XVVOERDUTLJJHN-UHFFFAOYSA-N
SMILES	CCC(C)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(N)Cc1c[nH]cn1)C(C)O)C(C)O)C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCCC1C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(N)=O
Storage condition	-20°C

Synonyms

ZP 10

AVE 0010

ZP10A peptide

lixisenatide

des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)- peptidylpenta-L-lysyl-L-lysinamide

AVE0010

Lyxumia

UNII-74O62BB01U

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