CAS 987-24-6|Betamethasone Acetate

Introduction：Basic information about CAS 987-24-6|Betamethasone Acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Betamethasone Acetate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles2
6. Synonyms

Common Name	Betamethasone Acetate
CAS Number	987-24-6	Molecular Weight	434.498
Density	1.3±0.1 g/cm3	Boiling Point	579.4±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₁FO₆	Melting Point	200-220°C (dec.)
MSDS	/	Flash Point	304.2±30.1 °C
Symbol	GHS08	Signal Word	Warning

Names

Name	betamethasone acetate
Synonym	More Synonyms

Betamethasone Acetate BiologicalActivity

Description	Betamethasone acetate is a glucocorticoid corticosteroid. Betamethasone acetate induces fetal lung maturation in preterm sheep[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Schmidt AF, et al. Low-dose betamethasone-acetate for fetal lung maturation in preterm sheep. Am J Obstet Gynecol. 2018 Jan;218(1):132.e1-132.e9.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	579.4±50.0 °C at 760 mmHg
Melting Point	200-220°C (dec.)
Molecular Formula	C₂₄H₃₁FO₆
Molecular Weight	434.498
Flash Point	304.2±30.1 °C
Exact Mass	434.210480
PSA	100.90000
LogP	2.96
Vapour Pressure	0.0±3.6 mmHg at 25°C
Index of Refraction	1.571
InChIKey	AKUJBENLRBOFTD-QZIXMDIESA-N
SMILES	CC(=O)OCC(=O)C1(O)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC21C
Storage condition	Refrigerator

Safety Information

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H351
Precautionary Statements	P280
Hazard Codes	Xn:Harmful
Risk Phrases	R40
Safety Phrases	S22-S36
RIDADR	NONH for all modes of transport
WGK Germany	3

Articles2

Differential cytotoxicity of corticosteroids on human mesenchymal stem cells.

Clin. Orthop. Relat. Res. 473(3) , 1155-64, (2015)

Corticosteroids are a common, short-term, local antiinflammatory and analgesic for treating patients with musculoskeletal disorders. Studies have shown the deleterious effects of corticosteroids on ch...

Andrejus Korolkovas

ESSENTIALS OF MEDICINAL CHEMISTRY 2nd ed.,, 1044, (2008)

Synonyms

Betamethasone acetate

MFCD00867462

(11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate

Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(acetyloxy)-, (11β,16β)-

Betafluorene

Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16β)-

UNII-TI05AO53L7

2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl acetate

9-Fluoro-11b,17,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione 21-Acetate

EINECS 213-578-6

Betamethasone 21-acetate

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