CAS 101-86-0|Hexyl cinnamaldehyde
| Common Name | Hexyl cinnamaldehyde | ||
|---|---|---|---|
| CAS Number | 101-86-0 | Molecular Weight | 216.319 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 308.1±0.0 °C at 760 mmHg |
| Molecular Formula | C15H20O | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 140.5±14.6 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | α-hexylcinnamaldehyde |
|---|---|
| Synonym | More Synonyms |
Hexyl cinnamaldehyde BiologicalActivity
| Description | α-Hexylcinnamaldehyde, a compound derived from Cinnamaldehyde. α-Hexylcinnamaldehyde has the potential antimutagenic and chemosensitizing properties. α-Hexylcinnamaldehyde is widely used as an ingredient in many personal care, and as an additive in food and the pharmaceutical industry[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| References | [1]. Maria Grazia Sarpietro, et al. Interaction of α-Hexylcinnamaldehyde with a Biomembrane Model: A Possible MDR Reversal Mechanism. J Nat Prod. 2015 May 22;78(5):1154-9. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 308.1±0.0 °C at 760 mmHg |
| Molecular Formula | C15H20O |
| Molecular Weight | 216.319 |
| Flash Point | 140.5±14.6 °C |
| Exact Mass | 216.151413 |
| PSA | 17.07000 |
| LogP | 5.33 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.530 |
| InChIKey | GUUHFMWKWLOQMM-QINSGFPZSA-N |
| SMILES | CCCCCCC(C=O)=Cc1ccccc1 |
| Storage condition | 2-8°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,915,1974
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,915,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(6),86,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6658 No. of Facilities: 2796 (estimated) No. of Industries: 11 No. of Occupations: 19 No. of Employees: 46014 (estimated) No. of Female Employees: 25863 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C:Corrosive |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45-S36 |
| RIDADR | UN 3265 8/PG 3 |
| WGK Germany | 2 |
| RTECS | GD6560000 |
| HS Code | 2912299000 |
Customs
| HS Code | 2912299000 |
|---|---|
| Summary | 2912299000. other cyclic aldehydes without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
Articles18
More Articles| Natural ingredients based cosmetics. Content of selected fragrance sensitizers. Contact Dermatitis 34(6) , 423-6, (1996) In the present study, we have investigated 42 cosmetic products based on natural ingredients for content of 11 fragrance substances: geraniol, hydroxycitronellal, eugenol, isoeugenol, cinnamic aldehyd... | |
| Evaluation of an ex vivo murine local lymph node assay: multiple endpoint comparison. J. Appl. Toxicol. 26(4) , 333-40, (2006) The local lymph node assay (LLNA) is used to assess the skin sensitization potential of chemicals. In the standard assay, mice are treated topically on the dorsum of both ears with test substance for ... | |
| Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix. Contact Dermatitis 52(4) , 207-15, (2005) The currently used 8% fragrance mix (FM I) does not identify all patients with a positive history of adverse reactions to fragrances. A new FM II with 6 frequently used chemicals was evaluated in 1701... |
Synonyms
| EINECS 202-983-3 |
| 2-Hexyl-3-phenyl-2-propenal |
| Octanal, 2-(phenylmethylene)-, (2E)- |
| α-hexyl cinnamaldehyde |
| JASMONAL H |
| α-Hexylcinnamic aldehyde |
| MFCD00006989 |
| (2E)-2-Benzylideneoctanal |
| α-Hexylcinnamaldehyde |
| 2-hexyl-3-phenylpropenal |
| FEMA 2569 |
| Hexyl cinnamal |
| A-HEXYLCINNAMALDEHYDE |
| HCA |
| Hexyl cinnamaldehyde |
| (2E)-2-(phenylmethylidene)octanal |
| 3-phenyl-2-hexylprop-2-enal |
| Cinnamaldehyde, α-hexyl- |
| 2-Benzylideneoctanal |
| hexyl cinnamic aldehyde |
| HEXYLCINNAMALDEHYDE |
| alpha-hexylcinnamaldehyde |
| 2-Hexyl-3-phenylacrylaldehyde |
| Octanal, 2- (phenylmethylene)- |
| jasminolene |
