Introduction：Basic information about CAS 82186-77-4|Lumefantrine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Lumefantrine |
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| CAS Number | 82186-77-4 | Molecular Weight | 528.940 |
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| Density | 1.252 | Boiling Point | 642.5±55.0 °C at 760 mmHg |
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| Molecular Formula | C30H32Cl3NO | Melting Point | 129-131ºC |
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| MSDS | ChineseUSA | Flash Point | 342.3±31.5 °C |
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Names
| Name | lumefantrine |
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| Synonym | More Synonyms |
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Lumefantrine BiologicalActivity
| Description | Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs. |
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| Related Catalog | Signaling Pathways >>Autophagy >>AutophagySignaling Pathways >>Anti-infection >>ParasiteResearch Areas >>Infection |
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| References | [1]. Ndounga M, et al. Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malar J. 2015 Oct 29;14(1):423. |
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Chemical & Physical Properties
| Density | 1.252 |
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| Boiling Point | 642.5±55.0 °C at 760 mmHg |
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| Melting Point | 129-131ºC |
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| Molecular Formula | C30H32Cl3NO |
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| Molecular Weight | 528.940 |
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| Flash Point | 342.3±31.5 °C |
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| Exact Mass | 527.154968 |
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| PSA | 23.47000 |
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| LogP | 11.37 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.634 |
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| InChIKey | DYLGFOYVTXJFJP-MYYYXRDXSA-N |
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| SMILES | CCCCN(CCCC)CC(O)c1cc(Cl)cc2c1-c1ccc(Cl)cc1C2=Cc1ccc(Cl)cc1 |
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| Storage condition | Refrigerator |
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Safety Information
| RIDADR | NONH for all modes of transport |
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| HS Code | 2922199090 |
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Customs
| HS Code | 2922199090 |
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| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| (±)-2-(Dibutylamino)-1-((9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol |
| (±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol |
| (Z)-2-(Dibutylamino)-1-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol |
| Benflumetol |
| Lumefantrine |
| 2-(Dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol |
| 9H-Fluorene-4-methanol, 2,7-dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-, (9Z)- |
