CAS 79-41-4|Methacrylic acid
Introduction：Basic information about CAS 79-41-4|Methacrylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methacrylic acid | ||
|---|---|---|---|
| CAS Number | 79-41-4 | Molecular Weight | 86.089 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 160.5±0.0 °C at 760 mmHg |
| Molecular Formula | C4H6O2 | Melting Point | 16 °C |
| MSDS | ChineseUSA | Flash Point | 76.7±0.0 °C |
| Symbol | GHS05, GHS06 | Signal Word | Danger |
Names
| Name | methacrylic acid |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 160.5±0.0 °C at 760 mmHg |
| Melting Point | 16 °C |
| Molecular Formula | C4H6O2 |
| Molecular Weight | 86.089 |
| Flash Point | 76.7±0.0 °C |
| Exact Mass | 86.036781 |
| PSA | 37.30000 |
| LogP | 0.83 |
| Vapour density | >3 (vs air) |
| Vapour Pressure | 1.2±0.6 mmHg at 25°C |
| Index of Refraction | 1.430 |
| InChIKey | CERQOIWHTDAKMF-UHFFFAOYSA-N |
| SMILES | C=C(C)C(=O)O |
| Stability | May be stabilized by the addition of MEHQ (Hydroquinone methyl ether, ca. 250 ppm) or hydroquinone. In the absence of a stabilizer this material will readily polymerize. Combustible. Incompatible with strong oxidizing agents, hydrochloric acid. |
| Water Solubility | 9.7 g/100 mL (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1060 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 95200 nL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 910 mg/kg/26W-I
- TOXIC EFFECTS :
- Behavioral - alteration of classical conditioning
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 221 mg/m3/24H/17W-C
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 221 mg/m3/24H/17W-C
- TOXIC EFFECTS :
- Behavioral - alteration of classical conditioning
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 910 mg/kg/26W-I
- TOXIC EFFECTS :
- Liver - liver function tests impaired Nutritional and Gross Metabolic - metabolic acidosis
MUTATION DATA - TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Bacteria - Escherichia coli
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981 *** REVIEWS *** ACGIH TLV-TWA 70 mg/m3 (20 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 11,141,1975 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-BELGIUM:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-DENMARK:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-FRANCE:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-GERMANY:TWA 50 ppm (210 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-RUSSIA:STEL 101 mg/m3;Skin JAN 1993 OEL-SWEDEN:TWA 20 ppm (70 mg/m3);STEL 30 ppm (100 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 20 ppm (70 mg/m3);STEL 40 ppm (140 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO METHACRYLIC ACID-air:10H TWA 20 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3304 No. of Facilities: 1529 (estimated) No. of Industries: 12 No. of Occupations: 31 No. of Employees: 18977 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3304 No. of Facilities: 10110 (estimated) No. of Industries: 109 No. of Occupations: 75 No. of Employees: 145414 (estimated) No. of Female Employees: 46453 (estimated)
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Bacteria - Escherichia coli
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981 *** REVIEWS *** ACGIH TLV-TWA 70 mg/m3 (20 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 11,141,1975 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-BELGIUM:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-DENMARK:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-FRANCE:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-GERMANY:TWA 50 ppm (210 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-RUSSIA:STEL 101 mg/m3;Skin JAN 1993 OEL-SWEDEN:TWA 20 ppm (70 mg/m3);STEL 30 ppm (100 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 20 ppm (70 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 20 ppm (70 mg/m3);STEL 40 ppm (140 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO METHACRYLIC ACID-air:10H TWA 20 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3304 No. of Facilities: 1529 (estimated) No. of Industries: 12 No. of Occupations: 31 No. of Employees: 18977 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3304 No. of Facilities: 10110 (estimated) No. of Industries: 109 No. of Occupations: 75 No. of Employees: 145414 (estimated) No. of Female Employees: 46453 (estimated)
Safety Information
| Symbol | GHS05, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302 + H332-H311-H314-H335 |
| Precautionary Statements | P261-P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C:Corrosive |
| Risk Phrases | R21/22;R35 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 2531 8/PG 2 |
| WGK Germany | 1 |
| RTECS | OZ2975000 |
| Packaging Group | II |
| Hazard Class | 8 |
| HS Code | 2916130010 |
Customs
| HS Code | 2916130010 |
|---|---|
| Summary | HS: 2916130010. methacrylic acid. VAT:17.0%. tax rebate rate:13.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tarrif:6.5%. general tariff:80.0% |
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Synonyms
| Loctite3298 |
| 2-methylprop-2-enoic acid |
| FX668F |
| a-Methylacrylic Acid |
| Methacrylic acid |
| acidometacrilico |
| 2-Propenoic acid, 2-methyl- |
| CH2=C(CH3)COOH |
| METAACRYLIC ACID |
| EINECS 201-204-4 |
| 2-methylpropenoic acid |
| 2-Methylene propionic acid |
| 2-Propenoic acid, 2-methyl-, endo- |
| 2-methylacrylic acid |
| acidemethacrylique |
| (methyl)acrylic acid |
| GE110 |
| methylcrotonic acid |
| MFCD00002651 |
