Introduction:Basic information about CAS 33889-68-8|Demethyl tetrandrine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Demethyl tetrandrine |
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| CAS Number | 33889-68-8 | Molecular Weight | 608.723 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 709.7±60.0 °C at 760 mmHg |
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| Molecular Formula | C37H40N2O6 | Melting Point | / |
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| MSDS | / | Flash Point | 383.0±32.9 °C |
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Names
| Name | Fangchinoline |
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| Synonym | More Synonyms |
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Demethyl tetrandrine BiologicalActivity
| Description | (R)-Fangchinoline (Thalrugosine), a alkaloids from genus Stephania,exhibits antimicrobial and hypotensive activity. The roots and stems of several plants from genus Stephania are all used as traditional Chinese medicine and have been used for treatment of fever, diarrhea, dyspepsia and urinary disease[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Xiao J, et al. Rapid characterization of TCM Qianjinteng by UPLC-QTOF-MS and its application in the evaluation of three species of Stephania. J Pharm Biomed Anal. 2018 Jul 15;156:284-296. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 709.7±60.0 °C at 760 mmHg |
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| Molecular Formula | C37H40N2O6 |
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| Molecular Weight | 608.723 |
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| Flash Point | 383.0±32.9 °C |
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| Exact Mass | 608.288635 |
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| PSA | 72.86000 |
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| LogP | 3.78 |
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| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
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| Index of Refraction | 1.602 |
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| InChIKey | IIQSJHUEZBTSAT-UHFFFAOYSA-N |
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| SMILES | COc1ccc2cc1Oc1ccc(cc1)CC1c3cc(c(OC)cc3CCN1C)Oc1c(O)c(OC)cc3c1C(C2)N(C)CC3 |
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Synonyms
| Berbaman-7-ol, 6,6',12-trimethoxy-2,2'-dimethyl- |
| (S,S)-(+)-tetrandine |
| (1β)-6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol |
| Fangquinoline |
| 6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol |
| N1799 |
| I06-1344 |
| THALRUGOSINE |
| FF-0018 |
| Fangchinoline |
| d,l-Fangchinolin |