CAS 33889-68-8|Demethyl tetrandrine

Introduction:Basic information about CAS 33889-68-8|Demethyl tetrandrine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDemethyl tetrandrine
CAS Number33889-68-8Molecular Weight608.723
Density1.2±0.1 g/cm3Boiling Point709.7±60.0 °C at 760 mmHg
Molecular FormulaC37H40N2O6Melting Point/
MSDS/Flash Point383.0±32.9 °C

Names

NameFangchinoline
SynonymMore Synonyms

Demethyl tetrandrine BiologicalActivity

Description(R)-Fangchinoline (Thalrugosine), a alkaloids from genus Stephania,exhibits antimicrobial and hypotensive activity. The roots and stems of several plants from genus Stephania are all used as traditional Chinese medicine and have been used for treatment of fever, diarrhea, dyspepsia and urinary disease[1].
Related CatalogResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References

[1]. Xiao J, et al. Rapid characterization of TCM Qianjinteng by UPLC-QTOF-MS and its application in the evaluation of three species of Stephania. J Pharm Biomed Anal. 2018 Jul 15;156:284-296.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point709.7±60.0 °C at 760 mmHg
Molecular FormulaC37H40N2O6
Molecular Weight608.723
Flash Point383.0±32.9 °C
Exact Mass608.288635
PSA72.86000
LogP3.78
Vapour Pressure0.0±2.3 mmHg at 25°C
Index of Refraction1.602
InChIKeyIIQSJHUEZBTSAT-UHFFFAOYSA-N
SMILESCOc1ccc2cc1Oc1ccc(cc1)CC1c3cc(c(OC)cc3CCN1C)Oc1c(O)c(OC)cc3c1C(C2)N(C)CC3

Synonyms

Berbaman-7-ol, 6,6',12-trimethoxy-2,2'-dimethyl-
(S,S)-(+)-tetrandine
(1β)-6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol
Fangquinoline
6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol
N1799
I06-1344
THALRUGOSINE
FF-0018
Fangchinoline
d,l-Fangchinolin
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