Introduction：Basic information about CAS 50402-56-7|EDANS, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | EDANS |
|---|
| CAS Number | 50402-56-7 | Molecular Weight | 266.31600 |
|---|
| Density | 1.432 g/cm3 | Boiling Point | / |
|---|
| Molecular Formula | C12H14N2O3S | Melting Point | >350°C |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid |
|---|
| Synonym | More Synonyms |
|---|
EDANS BiologicalActivity
| Description | EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET)[1]. |
|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
|---|
| In Vitro | The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR[1]. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis[1]. |
|---|
| References | [1]. E D Matayoshi, et al. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer. Science. 1990 Feb 23;247(4945):954-8. |
|---|
Chemical & Physical Properties
| Density | 1.432 g/cm3 |
|---|
| Melting Point | >350°C |
|---|
| Molecular Formula | C12H14N2O3S |
|---|
| Molecular Weight | 266.31600 |
|---|
| Exact Mass | 266.07300 |
|---|
| PSA | 100.80000 |
|---|
| LogP | 3.31120 |
|---|
| Index of Refraction | 1.691 |
|---|
| InChIKey | SJQRQOKXQKVJGJ-UHFFFAOYSA-N |
|---|
| SMILES | NCCNc1cccc2c(S(=O)(=O)O)cccc12 |
|---|
| Storage condition | Refrigerator |
|---|
Safety Information
| Hazard Codes | Xn: Harmful; |
|---|
| Risk Phrases | 22-36/37/38-43 |
|---|
| Safety Phrases | S26-S27-S36/37/39-S45 |
|---|
| WGK Germany | 3 |
|---|
| HS Code | 2921590090 |
|---|
Customs
| HS Code | 2921590090 |
|---|
| Summary | 2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
|---|
Synonyms
| 5-(2-Aminoethylamino)-1-naphthalenesulfonic acid |
| 1,5-EDANS (N-(Aminoethyl)-5-naphthylamine-1-sulfonic acid |
| 5-(2-aminoethylamino)naphthalene-1-sulfonic acid |
| MFCD00066932 |
| EINECS 256-575-5 |
