Introduction：Basic information about CAS 6361-21-3|2-Chloro-5-nitrobenzaldehyde, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Chloro-5-nitrobenzaldehyde |
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| CAS Number | 6361-21-3 | Molecular Weight | 185.565 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 290.3±25.0 °C at 760 mmHg |
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| Molecular Formula | C7H4ClNO3 | Melting Point | 75-77 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 129.4±23.2 °C |
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Names
| Name | 2-Chloro-5-nitrobenzaldehyde |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 290.3±25.0 °C at 760 mmHg |
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| Melting Point | 75-77 °C(lit.) |
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| Molecular Formula | C7H4ClNO3 |
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| Molecular Weight | 185.565 |
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| Flash Point | 129.4±23.2 °C |
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| Exact Mass | 184.987976 |
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| PSA | 62.89000 |
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| LogP | 2.50 |
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| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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| Index of Refraction | 1.630 |
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| InChIKey | VFVHWCKUHAEDMY-UHFFFAOYSA-N |
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| SMILES | O=Cc1cc([N+](=O)[O-])ccc1Cl |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- CU5220000
- CHEMICAL NAME :
- Benzaldehyde, 2-chloro-5-nitro-
- CAS REGISTRY NUMBER :
- 6361-21-3
- BEILSTEIN REFERENCE NO. :
- 0743764
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C7-H4-Cl-N-O3
- MOLECULAR WEIGHT :
- 185.57
- WISWESSER LINE NOTATION :
- WNR DG CVH
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555310
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555310
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00052 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12390 mg/kg/14D-C
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Endocrine - changes in thyroid weight Blood - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555310
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S22-S24/25-S37/39-S26 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 2 |
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| RTECS | CU5220000 |
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Articles3
More Articles
| (E,Z)-2-(2-chloro-5-nitrostyryl)-1-(1-propenyl)benzimidazole. Acta Crystallogr. C 53 ( Pt 7) , 907-9, (1997) The title compound, C18H14ClN3O2, was synthesized by the condensation of 2-chloro-5-nitrobenzaldehyde with 2-methyl-1-propenylbenzimidazole, and the molecule comprises a 2-chloro-5-nitrobenzene and a ... | |
| Morita-Baylis-Hillman route to 4H-pyrrolo [1, 2-a][1] benzazepine derivatives. Park SP, et al. Tetrahedron 65(24) , 4703-4708, (2009)
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| Reactions of 5-amino-1, 2-azoles with aromatic and heterocyclic o-chloroaldehydes:[1+ 1] versus [2+ 1] cyclocondensation. Abramov MA, et al. Tetrahedron 57(44) , 9123-9129, (2001)
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Synonyms
| 2-Chloro-5-nitrobenzaldehyde |
| MFCD00007293 |
| EINECS 228-830-0 |
| Benzaldehyde, 2-chloro-5-nitro- |
