Introduction：Basic information about CAS 494-79-1|melarsoprol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | melarsoprol |
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| CAS Number | 494-79-1 | Molecular Weight | 398.33900 |
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| Density | / | Boiling Point | 688.4ºC at 760 mmHg |
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| Molecular Formula | C12H15AsN6OS2 | Melting Point | / |
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| MSDS | / | Flash Point | 370.2ºC |
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Names
| Name | [2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol |
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| Synonym | More Synonyms |
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melarsoprol BiologicalActivity
| Description | Melarsoprol (Arsobal), a melaminophenylarsine-type trivalent organic arsenical, is an important drug for African trypanosomiasis. Melarsoprol is also active against leukemia cell lines and plasma cells from myeloma patients. Melarsoprol increases the biliary output of GSH in rats[1]. |
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| Related Catalog | Research Areas >>Infection |
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| References | [1]. Z Gregus, et al. Role of glutathione in the biliary excretion of the arsenical drugs trimelarsan and melarsoprol. Biochem Pharmacol. 2000 Jun 1;59(11):1375-85. |
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Chemical & Physical Properties
| Boiling Point | 688.4ºC at 760 mmHg |
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| Molecular Formula | C12H15AsN6OS2 |
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| Molecular Weight | 398.33900 |
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| Flash Point | 370.2ºC |
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| Exact Mass | 397.99600 |
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| PSA | 173.57000 |
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| LogP | 1.55110 |
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| Vapour Pressure | 6.7E-20mmHg at 25°C |
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| InChIKey | JCYZMTMYPZHVBF-UHFFFAOYSA-N |
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| SMILES | Nc1nc(N)nc(Nc2ccc([As]3SCC(CO)S3)cc2)n1 |
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Synonyms
| Mel B |
| melarsenoxide-BAL |
| Melarsoprol |
| Melarsoprolum [INN-Latin] |
| Melarsoprolum |
| 2-(p-(4,6-Diamino-s-triazin-2-ylamino)phenyl)-1,3,2-dithiarsolane-4-methanol |
| {2-[4-(4,6-diamino-[1,3,5]triazin-2-ylamino)-phenyl]-[1,3,2]dithiarsolan-4-yl}-methanol |
| EINECS 207-793-4 |
| Melarsenoxid-BAL |
| 1,3,2-Dithiarsolane-4-methanol,2-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl) |
| Arsobal |
