Introduction：Basic information about CAS 79352-78-6|N-Desethyl amodiaquine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Desethyl amodiaquine |
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| CAS Number | 79352-78-6 | Molecular Weight | 327.81 |
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| Density | 1.304g/cm3 | Boiling Point | 477.8ºC at 760 mmHg |
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| Molecular Formula | C18H18ClN3O | Melting Point | 168-174ºC |
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| MSDS | / | Flash Point | 242.7ºC |
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Names
| Name | n-desethyl amodiaquine dihcl |
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| Synonym | More Synonyms |
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N-Desethyl amodiaquine BiologicalActivity
| Description | N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteResearch Areas >>Infection |
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| References | [1]. Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82. |
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Chemical & Physical Properties
| Density | 1.304g/cm3 |
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| Boiling Point | 477.8ºC at 760 mmHg |
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| Melting Point | 168-174ºC |
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| Molecular Formula | C18H18ClN3O |
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| Molecular Weight | 327.81 |
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| Flash Point | 242.7ºC |
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| Exact Mass | 332.14500 |
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| PSA | 57.18000 |
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| LogP | 4.91080 |
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| Index of Refraction | 1.69 |
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| InChIKey | VRXFDHAGFYWGHT-UHFFFAOYSA-N |
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| SMILES | CCNCc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O |
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Synonyms
| N-Desethylamodiaquine |
| 4-[(7-Chloro-4-quinolinyl)aMino]-2-[(ethylaMino)Methyl]phenol |
| N-de-ethyl amodiaquine |
| Desethylamodiaquine-[2H5] |
| 4-[(7-Chloro-4-quinolyl)amino]-2-aminomethylphenol |
| N-Desethylamodiaquine dihydrochloride |
| desethylamodiaquine |
