CAS 471-74-9|Sandaracopimaric acid

Introduction：Basic information about CAS 471-74-9|Sandaracopimaric acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Sandaracopimaric acid BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Sandaracopimaric acid
CAS Number	471-74-9	Molecular Weight	302.451
Density	1.1±0.1 g/cm3	Boiling Point	413.2±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₀O₂	Melting Point	/
MSDS	/	Flash Point	198.7±23.4 °C

Names

Name	.δ.8(14)-Isopimaric acid
Synonym	More Synonyms

Sandaracopimaric acid BiologicalActivity

Description	Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].
Related Catalog	Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Wenyan Gao, et al. Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway. Molecules. 2014 Jun 23;19(6):8503-17. [2]. Masao Takei, et al. Diterpenes drive Th1 polarization depending on IL-12. Int Immunopharmacol. 2008 Nov;8(11):1602-8.

Description

Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].

Related Catalog

Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology

References

[1]. Wenyan Gao, et al. Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway. Molecules. 2014 Jun 23;19(6):8503-17.

[2]. Masao Takei, et al. Diterpenes drive Th1 polarization depending on IL-12. Int Immunopharmacol. 2008 Nov;8(11):1602-8.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	413.2±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₀O₂
Molecular Weight	302.451
Flash Point	198.7±23.4 °C
Exact Mass	302.224579
PSA	37.30000
LogP	6.60
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.538
InChIKey	MHVJRKBZMUDEEV-KRFUXDQASA-N
SMILES	C=CC1(C)C=C2CCC3C(C)(C(=O)O)CCCC3(C)C2CC1

Synonyms

Pimara-8(14),15-dien-18-oic acid

(ent)-pimara-8(14),15-dien-19-oic acid

pimaradienoic acid

(-)-pimara-8(14),15-diene-19-oic acid

1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-

7-Ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylic Acid

13-Methyl-17-norabieta-8(14),15-diene-18-oic acid

(-)-pimara-8(14),15-dien-19-oic acid

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