CAS 34523-34-7|4-Hydroxyacetophenone oxime

Introduction：Basic information about CAS 34523-34-7|4-Hydroxyacetophenone oxime, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name4-Hydroxyacetophenone oxime
CAS Number34523-34-7Molecular Weight151.16300
Density1.246g/cm3Boiling Point294.8ºC at 760mmHg
Molecular FormulaC8H9NO2Melting Point143 °C
MSDS/Flash Point132.1ºC

Names

Name4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one
SynonymMore Synonyms

4-Hydroxyacetophenone oxime BiologicalActivity

Description4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic drug[1][2].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References

[1]. Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22(2): p. 383-90.

[2]. Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8(6):553-9.

Chemical & Physical Properties

Density1.246g/cm3
Boiling Point294.8ºC at 760mmHg
Melting Point143 °C
Molecular FormulaC8H9NO2
Molecular Weight151.16300
Flash Point132.1ºC
Exact Mass151.06300
PSA52.82000
LogP1.59040
Index of Refraction1.591
InChIKeyBVZSQTRWIYKUSF-UHFFFAOYSA-N
SMILESCC(=NO)c1ccc(O)cc1

Safety Information

Hazard CodesXn
HS Code2928000090

Customs

HS Code2928000090
Summary2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Synonyms

p-hydroxyacetophenone oxime
4-hydroxyphenyl methyl ketone oxime
methyl p-hydroxyphenyl ketone oxime
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