CAS 18829-70-4|(-)-catechin
| Common Name | (-)-catechin | ||
|---|---|---|---|
| CAS Number | 18829-70-4 | Molecular Weight | 290.26800 |
| Density | 1.593 g/cm3 | Boiling Point | 630.4ºC at 760 mmHg |
| Molecular Formula | C15H14O6 | Melting Point | 175-176ºC |
| MSDS | ChineseUSA | Flash Point | 335ºC |
Names
| Name | (-)-catechin |
|---|---|
| Synonym | More Synonyms |
(-)-catechin BiologicalActivity
| Description | (-)-Catechin, isolated from green tea, is an isomer of Catechin having a trans 2S,3R configuration at the chiral center. Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Immunology/Inflammation >>COX |
| References | [1]. Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9. |
Chemical & Physical Properties
| Density | 1.593 g/cm3 |
|---|---|
| Boiling Point | 630.4ºC at 760 mmHg |
| Melting Point | 175-176ºC |
| Molecular Formula | C15H14O6 |
| Molecular Weight | 290.26800 |
| Flash Point | 335ºC |
| Exact Mass | 290.07900 |
| PSA | 110.38000 |
| LogP | 1.54610 |
| Vapour Pressure | 1.09E-20mmHg at 25°C |
| InChIKey | PFTAWBLQPZVEMU-HIFRSBDPSA-N |
| SMILES | Oc1cc(O)c2c(c1)OC(c1ccc(O)c(O)c1)C(O)C2 |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles11
More Articles| An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. J. Nat. Prod. 73 , 1193-5, (2010) Antioxidants scavenge free radicals, singlet oxygen, and electrons in cellular redox reactions. The yellow MTT [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide] is reduced to a purple fo... | |
| The blood pressure effect and related plasma levels of flavan-3-ols in spontaneously hypertensive rats. Food Funct. 6 , 3479-89, (2015) We studied the short-term antihypertensive effect of flavan-3-ols (-)-epicatechin, (+)-catechin and (-)-catechin, in spontaneously hypertensive rats (SHR). Plasma metabolites and the corresponding pla... | |
| Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi. Eur. J. Med. Chem. 50 , 230-5, (2012) Bioassay guided fractionation of ethanolic extract of the leaves of Bauhinia racemosa led to the isolation of galactolipid and catechin class of the compounds (1-7) from the most active n-butanol frac... |
Synonyms
| ent-catechin |
| (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol |
| MFCD00180760 |
| (-)-Catechin |
| EINECS 242-611-7 |
| (−)-Catechin |
| Catechin l-form |
