CAS 98-55-5|Terpineol
| Common Name | Terpineol | ||
|---|---|---|---|
| CAS Number | 98-55-5 | Molecular Weight | 154.249 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 217.5±0.0 °C at 760 mmHg |
| Molecular Formula | C10H18O | Melting Point | 31-34ºC |
| MSDS | ChineseUSA | Flash Point | 89.4±0.0 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | α-terpineol |
|---|---|
| Synonym | More Synonyms |
Terpineol BiologicalActivity
| Description | α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria[1].α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption[2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Park SN, et al. Antimicrobial effect of linalool and α-terpineol against periodontopathic and cariogenic bacteria. Anaerobe. 2012 Jun;18(3):369-72. [2]. Park MJ, et al. Effect of citral, eugenol, nerolidol and alpha-terpineol on the ultrastructural changes of Trichophyton mentagrophytes. Fitoterapia. 2009 Jul;80(5):290-6. |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 217.5±0.0 °C at 760 mmHg |
| Melting Point | 31-34ºC |
| Molecular Formula | C10H18O |
| Molecular Weight | 154.249 |
| Flash Point | 89.4±0.0 °C |
| Exact Mass | 154.135757 |
| PSA | 20.23000 |
| LogP | 2.79 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.483 |
| InChIKey | WUOACPNHFRMFPN-UHFFFAOYSA-N |
| SMILES | CC1=CCC(C(C)(C)O)CC1 |
| Storage condition | 2-8°C |
| Water Solubility | negligible |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5170 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 31(2),29,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2830 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 33,1669,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JSICAZ Journal of Scientific and Industrial Research, Section C: Biological Sciences. (New Delhi, India) V.14-21, 1955-62. For publisher information, see IJEBA6. Volume(issue)/page/year: 21,342,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7755 mg/kg/30D-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 31(2),29,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80268 No. of Facilities: 2241 (estimated) No. of Industries: 37 No. of Occupations: 47 No. of Employees: 16136 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80268 No. of Facilities: 20420 (estimated) No. of Industries: 125 No. of Occupations: 102 No. of Employees: 328085 (estimated) No. of Female Employees: 125759 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R38 |
| Safety Phrases | S37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | WZ6700000 |
| HS Code | 29061400 |
Customs
| HS Code | 2906199090 |
|---|---|
| Summary | 2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
Articles34
More Articles| Terpinen-4-ol and alpha-terpineol (tea tree oil components) inhibit the production of IL-1β, IL-6 and IL-10 on human macrophages. Inflamm. Res. 63(9) , 769-78, (2014) Tea tree oil (TTO) is an essential oil with anti-inflammatory properties, steam distilled from the plant Melaleuca alternifolia. We investigated the immunomodulatory properties of TTO and its componen... | |
| Activation of human 5-hydroxytryptamine type 3 receptors via an allosteric transmembrane site. Mol. Pharmacol. 87(1) , 87-95, (2015) In common with other members of the Cys-loop family of pentameric ligand-gated ion channels, 5-hydroxytryptamine type 3 receptors (5-HT3Rs) are activated by the binding of a neurotransmitter to an ext... | |
| Evaluation of the antioxidant and antiproliferative potential of bioflavors Food Chem. Toxicol. 49(7) , 1610-5, (2011) Highlights ► Antioxidant potential and antiproliferative effect of five monoterpenes was investigated. ► α-Terpineol presented good antioxidant activity in ORAC test. ► Limonene and α-terpineol presen... |
Synonyms
| TERPINENOL |
| 2-(4-Methyl-3-cyclohexen-1-yl)-2-propanol |
| alpha-terpineol |
| pc593 |
| MFCD00001557 |
| 3-Cyclohexene-1-methanol, α,α,4-trimethyl- |
| TILIANOL NP |
| A-TERPINEOL |
| EINECS 232-268-1 |
| TERPINEOL BP |
| TERPINEOL N |
| Terpineol schlechthin |
| Terpenol |
| p-menth-1-en-8-ol |
| L6UTJ A1 DXQ1&1 |
| α-Terpineol |
| Terpilenol |
