CAS 181477-43-0|(Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetat

Introduction：Basic information about CAS 181477-43-0|(Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetat, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	(Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetate salt
CAS Number	181477-43-0	Molecular Weight	1035.21
Density	1.3±0.1 g/cm3	Boiling Point	1450.7±65.0 °C at 760 mmHg
Molecular Formula	C₄₇H₇₄N₁₀O₁₄S	Melting Point	/
MSDS	/	Flash Point	831.1±34.3 °C

Names

Name	Disomotide
Synonym	More Synonyms

BiologicalActivity

Description	Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma[1][2].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
In Vitro	为了激活 Ag，用 Disomotide (G209-2M; 1 μM) 处理 PBMCs 6天[2]。
References	[1]. Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9. [2]. Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	1450.7±65.0 °C at 760 mmHg
Molecular Formula	C₄₇H₇₄N₁₀O₁₄S
Molecular Weight	1035.21
Flash Point	831.1±34.3 °C
Exact Mass	1034.510620
PSA	413.25000
LogP	2.44
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.569
InChIKey	BDQMCYCLZBSYJZ-UHFFFAOYSA-N
SMILES	CCC(C)C(N)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CCC(N)=O)C(=O)NC(C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)NC(C(=O)O)C(C)C)C(C)C

Synonyms

disomotide

L-Isoleucyl-L-methionyl-L-α-aspartyl-L-glutaminyl-L-valyl-L-prolyl-L-phenylalanyl-L-seryl-L-valine

L-Valine, L-isoleucyl-L-methionyl-L-α-aspartyl-L-glutaminyl-L-valyl-L-prolyl-L-phenylalanyl-L-seryl-

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