CAS 343306-71-8|Sugammadex
Introduction：Basic information about CAS 343306-71-8|Sugammadex, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sugammadex | ||
|---|---|---|---|
| CAS Number | 343306-71-8 | Molecular Weight | 2002.151 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C72H104Na8O48S8 | Melting Point | / |
| MSDS | / | Flash Point | / |
Names
| Name | Org 25969 |
|---|---|
| Synonym | More Synonyms |
Sugammadex BiologicalActivity
| Description | Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| In Vivo | Sugammadex (100 mg/kg, IV, once) has a nephroprotective effect when given at the beginning of reperfusion after one hour of ischemic condition on rats[2]. |
| References | [1]. de Boer HD, et al. Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey. Br J Anaesth. 2006 Apr;96(4):473-9. Epub 2006 Feb 7. [2]. Tercan M, Yılmaz İnal F, Seneldir H, Kocoglu H. Nephroprotective Efficacy of Sugammadex in Ischemia-Reperfusion Injury: An Experimental Study in a Rat Model. Cureus. 2021 Jun 17;13(6):e15726. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C72H104Na8O48S8 |
| Molecular Weight | 2002.151 |
| Exact Mass | 2000.408813 |
| PSA | 994.80000 |
| LogP | -1.25 |
| Index of Refraction | 1.610 |
| InChIKey | WHRODDIHRRDWEW-VTHZAVIASA-N |
| SMILES | O=C(O)CCSCC1OC2OC3C(CSCCC(=O)O)OC(OC4C(CSCCC(=O)O)OC(OC5C(CSCCC(=O)O)OC(OC6C(CSCCC(=O)O)OC(OC7C(CSCCC(=O)O)OC(OC8C(CSCCC(=O)O)OC(OC9C(CSCCC(=O)O)OC(OC1C(O)C2O)C(O)C9O)C(O)C8O)C(O)C7O)C(O)C6O)C(O)C5O)C(O)C4O)C(O)C3O |
Synonyms
| 3,3',3'',3''',3'''',3''''',3'''''',3'''''''-{[(1S,3S,5S,6S,8S,10S,11S,13S,15S,16S,18S,20S,21S,23S,25S,26S,28S,30S,31S,33S,35S,36S,38S,40S,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56 ;R)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-Hexadecahydroxy-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2.2.2.2.2.2.2]h exapentacontane-5,10,15,20,25,30,35,40-octay |
| cyclooctakis-(1&;rarr;4)-[6-S-(2-carboxyethyl)-6-thio-α-D-glucopyranosyl] |
| unii-361lpm2t56 |
| Sugammadex |
| UNII361LPM2T56 |
