Introduction：Basic information about CAS 181587-01-9|Ethiprole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ethiprole |
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| CAS Number | 181587-01-9 | Molecular Weight | 397.20300 |
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| Density | 1.69g/cm3 | Boiling Point | 563.5ºC at 760mmHg |
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| Molecular Formula | C13H9Cl2F3N4OS | Melting Point | ~174° |
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| MSDS | USA | Flash Point | 294.6ºC |
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| Symbol |
GHS08, GHS09 | Signal Word | Warning |
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Names
| Name | ethiprole |
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| Synonym | More Synonyms |
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Ethiprole BiologicalActivity
| Description | Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
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| References | [1]. Caboni P, Sammelson RE, Casida JE. Phenylpyrazole insecticide photochemistry, metabolism, and GABAergic action: ethiprole compared with fipronil. J Agric Food Chem. 2003 Nov 19;51(24):7055-61. |
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Chemical & Physical Properties
| Density | 1.69g/cm3 |
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| Boiling Point | 563.5ºC at 760mmHg |
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| Melting Point | ~174° |
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| Molecular Formula | C13H9Cl2F3N4OS |
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| Molecular Weight | 397.20300 |
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| Flash Point | 294.6ºC |
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| Exact Mass | 395.98300 |
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| PSA | 103.91000 |
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| LogP | 5.22618 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.655 |
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| InChIKey | FNELVJVBIYMIMC-UHFFFAOYSA-N |
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| SMILES | CCS(=O)c1c(C#N)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N |
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| Storage condition | 0-6°C |
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Safety Information
| Symbol |
GHS08, GHS09 |
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| Signal Word | Warning |
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| Hazard Statements | H373-H410 |
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| Precautionary Statements | P273-P501 |
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| Target Organs | Liver, Thyroid. |
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| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
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| Hazard Codes | T,N |
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| Risk Phrases | R23/24/25 |
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| Safety Phrases | S36/37 |
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| RIDADR | UN2811 6.1/PG 3 |
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Synonyms
| Ethiprole |
| UNII-5527E53JNB |
| 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile |
| 5-amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-ethylsulfinylpyrazole-3-carbonitrile |
| 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-ethylsulfinylpyrazole-3-carbonitrile |
| 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethanesulfinyl)-1H-pyrazole-3-carbonitrile |
