Introduction：Basic information about CAS 71617-10-2|Isoamyl 4-Methoxycinnamate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Isoamyl 4-Methoxycinnamate |
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| CAS Number | 71617-10-2 | Molecular Weight | 248.318 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 362.8±17.0 °C at 760 mmHg |
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| Molecular Formula | C15H20O3 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 151.6±15.5 °C |
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Names
| Name | Isoamyl 4-Methoxycinnamate |
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| Synonym | More Synonyms |
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Isoamyl 4-Methoxycinnamate BiologicalActivity
| Description | Amiloxate is a UV-filter with anti-inflammatory activity[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Amiloxate (isoamyl p-methoxycinnamate, 10% w/w) shows anti-inflammatory effect by inhibiting the edema (83%)[1]. |
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| References | [1]. Céline Couteau, et al. UV Filters, Ingredients with a Recognized Anti-Inflammatory Effect. PLoS One. 2012; 7(12): e46187. |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 362.8±17.0 °C at 760 mmHg |
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| Molecular Formula | C15H20O3 |
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| Molecular Weight | 248.318 |
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| Flash Point | 151.6±15.5 °C |
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| Exact Mass | 248.141251 |
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| PSA | 35.53000 |
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| LogP | 4.06 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.524 |
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| InChIKey | UBNYRXMKIIGMKK-RMKNXTFCSA-N |
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| SMILES | COc1ccc(C=CC(=O)OCCC(C)C)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UD3393500
- CHEMICAL NAME :
- 2-Propenoic acid, 3-(4-methoxyphenyl)-, 3-methylbutyl ester
- CAS REGISTRY NUMBER :
- 71617-10-2
- BEILSTEIN REFERENCE NO. :
- 3132627
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C15-H20-O3
- MOLECULAR WEIGHT :
- 248.35
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 30,803,1992
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >20 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 30,803,1992 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 22500 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 30,803,1992
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Safety Information
| Hazard Statements | H413 |
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| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 2.0 |
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| RTECS | UD3393500 |
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| HS Code | 2918990090 |
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Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Articles3
More Articles
| [Analysis of the volatile oils chemical constituents of roots of Actinidia deliciosa]. Zhong Yao Cai 31(5) , 677-8, (2008) To analyze the volatile oils chemical constituents of roots of Actinidia deliciosa.The volatile oils fraction of roots of Actinidia deliciosa. were extracted by water vapor distilling, and then the co... | |
| Embryotoxicity study of propenoic acid, 3-(4-methoxyphenyl)-3-methylbutylester in the Wistar rat. Food Chem. Toxicol. 30(9) , 803-7, (1992) 3-(4-methoxyphenyl)-3-methylbutylester, propenoic acid (MPMBE; CAS no. 71617-10-2), a UVB-light filter used for sun protection of the skin, was administered once daily by intragastric gavage to pregna... | |
| Photo-allergic contact dermatitis caused by isoamyl p-methoxycinnamate in an 'organic' sunscreen. Contact Dermatitis 64(2) , 115-6, (2011)
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Synonyms
| 3-(4-methoxyphenyl)-2-propenoic acid 3-methylbutyl ester |
| Neo Heliopan |
| isoamyl p-methoxycinnamate |
| 3-Methylbutyl (2E)-3-(4-methoxyphenyl)acrylate |
| amiloxate |
| Isoamyl 4-methoxycinnamate |
| Isopentyl 4-methoxycinnamate |
| 2-Propenoic acid, 3-(4-methoxyphenyl)-, 3-methylbutyl ester |
| isopentyl p-methoxycinnamate |
| 2-Propenoic acid, 3-(4-methoxyphenyl)-, 3-methylbutyl ester, (2E)- |
| 3-Methylbutyl 3-(4-methoxyphenyl)-2-propenoate |
| ISOPENTYL-4-METHOXYCINNAMATE |
| EINECS 275-702-5 |
