CAS 458-36-6|coniferyl aldehyde
| Common Name | coniferyl aldehyde | ||
|---|---|---|---|
| CAS Number | 458-36-6 | Molecular Weight | 178.185 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 338.8±27.0 °C at 760 mmHg |
| Molecular Formula | C10H10O3 | Melting Point | 80-82ºC(lit.) |
| MSDS | ChineseUSA | Flash Point | 136.8±17.2 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | coniferyl aldehyde |
|---|---|
| Synonym | More Synonyms |
coniferyl aldehyde BiologicalActivity
| Description | Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Kim KM, et al. Coniferaldehyde inhibits LPS-induced apoptosis through the PKC α/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Environ Toxicol Pharmacol. 2016 Dec;48:85-93. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 338.8±27.0 °C at 760 mmHg |
| Melting Point | 80-82ºC(lit.) |
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.185 |
| Flash Point | 136.8±17.2 °C |
| Exact Mass | 178.062988 |
| PSA | 46.53000 |
| LogP | 1.35 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.593 |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-37/39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2912499000 |
Customs
| HS Code | 2912499000 |
|---|---|
| Summary | 2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
Articles8
More Articles| A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry. J. Mass Spectrom. 49(8) , 665-73, (2014) Imaging mass spectrometry (IMS) studies increasingly focus on endogenous small molecular weight metabolites and consequently bring special analytical challenges. Since analytical tissue blanks do not ... | |
| Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry. J. Am. Soc. Mass Spectrom. 22(8) , 1409-19, (2011) Isoniazid (INH) is an important component of front-line anti-tuberculosis therapy with good serum pharmacokinetics but unknown ability to penetrate tuberculous lesions. However, endogenous background ... | |
| Antifungal synergistic effect of scopoletin, a hydroxycoumarin isolated from Melia azedarach L. fruits. J. Agric. Food Chem. 53(8) , 2922-7, (2005) In the continuous search for antifungal compounds from plants, the hydroxycoumarin scopoletin (1) was isolated from seed kernels of Melia azedarach L. from which three other compounds, vanillin (2), 4... |
Synonyms
| Ferulaldehyde |
| (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal |
| (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal |
| Ferulyl aldehyde |
| 2-Propenal, 3-(4-hydroxy-3-methoxyphenyl), (E)- |
| 4-hydroxy-3-methoxy-benzaldehyde |
| MFCD00075811 |
| 4-hydroxy-3-methoxy-cinnamon-aldehyde |
| 2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)- |
| coniferaldehyde |
| 4-hydroxy-3-methoxycinnamic aldehyde |
| EINECS 207-278-4 |
| 4-HYDROXY-3-METHOXYCINNAMALDEHYDE |
| (2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylaldehyde |
| coniferyl aldehyde |
| Coniferylaldehyde |
