CAS 98665-19-1|Ganoderic acid H

Introduction:Basic information about CAS 98665-19-1|Ganoderic acid H, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGanoderic acid H
CAS Number98665-19-1Molecular Weight572.69
Density1.25g/cm3Boiling Point710ºC at 760 mmHg
Molecular FormulaC32H44O9Melting Point155-156 °C
MSDS/Flash Point222.5ºC

Names

Name(2R,6S)-6-[(3S,5R,10S,12S,13R,14R,17R)-12-acetyloxy-3-hydroxy-4,4,10,13,14-pentamethyl-7,11,15-trioxo-1,2,3,5,6,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
SynonymMore Synonyms

Ganoderic acid H BiologicalActivity

DescriptionGanoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
References

[1]. Jiang J, et al. Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. Int J Mol Med. 2008 May;21(5):577-84.

Chemical & Physical Properties

Density1.25g/cm3
Boiling Point710ºC at 760 mmHg
Melting Point155-156 °C
Molecular FormulaC32H44O9
Molecular Weight572.69
Flash Point222.5ºC
PSA152.11000
LogP3.63530
Index of Refraction1.557
InChIKeyYCXUCEXEMJPDRZ-YIRLAGBYSA-N
SMILESCC(=O)OC1C(=O)C2=C(C(=O)CC3C2(C)CCC(O)C3(C)C)C2(C)C(=O)CC(C(C)CC(=O)CC(C)C(=O)O)C12C
Water SolubilityInsuluble (2.6E-3 g/L) (25 ºC)

Synonyms

Ganoderic acid H
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