CAS 6402-36-4|traumatic acid

Introduction:Basic information about CAS 6402-36-4|traumatic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nametraumatic acid
CAS Number6402-36-4Molecular Weight228.285
Density1.1±0.1 g/cm3Boiling Point376.4±15.0 °C at 760 mmHg
Molecular FormulaC12H20O4Melting Point165-167 °C(lit.)
MSDS/Flash Point195.6±16.9 °C

Names

Nametraumatic acid
SynonymMore Synonyms

traumatic acid BiologicalActivity

DescriptionTraumatic Acid is a monounsaturated dicarboxylic acid isolated from  Phaseolus vulgaris. Traumatic Acid can cause a decrease in membrane phospholipid peroxidation and show antioxidant and stimulatory effects on collagen biosynthesis. Traumatic Acid is a potential agent for the treatment of many skin diseases connected with collagen biosynthesis disorders and oxidative stress[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
Target

IC50: collagen biosynthesis[1]

References

[1]. Jabłońska-Trypuć A, et al. Traumatic Acid Reduces Oxidative Stress and Enhances Collagen Biosynthesis in Cultured Human Skin Fibroblasts.Lipids. 2016 Sep;51(9):1021-35.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point376.4±15.0 °C at 760 mmHg
Melting Point165-167 °C(lit.)
Molecular FormulaC12H20O4
Molecular Weight228.285
Flash Point195.6±16.9 °C
Exact Mass228.136154
PSA74.60000
LogP2.95
Vapour Pressure0.0±1.8 mmHg at 25°C
Index of Refraction1.493
InChIKeyMAZWDMBCPDUFDJ-VQHVLOKHSA-N
SMILESO=C(O)C=CCCCCCCCCC(=O)O
Storage condition2-8°C

Safety Information

Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
WGK Germany3

Synonyms

2-Dodecenedioic acid
Traumatic Acid
Dodec-2t-endisaeure
(2E)-Dodec-2-enedioic acid
2-dodecendioic acid
dodec-2-enedioic acid
trans-2-Dodecenedioic acid
traumatoic acid
EINECS 229-019-4
trans-Traumatinsaeure
trans-Traumatic acid
Taumatic acid
2E-DODECENEDIOIC ACID
(2E)-2-Dodecenedioic acid
1-Decene-1,10-dicarboxylic acid
2-Dodecenedioic acid, (2E)-
UNII:L7ND24937H
(2E)-Dodecenedioic acid
dodec-2t-enedioic acid
MFCD00004443
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