Introduction：Basic information about CAS 33817-20-8|pivampicillin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | pivampicillin |
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| CAS Number | 33817-20-8 | Molecular Weight | 463.55 |
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| Density | 1.33g/cm3 | Boiling Point | 679ºC at 760mmHg |
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| Molecular Formula | C22H29N3O6S | Melting Point | / |
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| MSDS | / | Flash Point | 364.5ºC |
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Names
| Name | pivampicillin |
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| Synonym | More Synonyms |
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pivampicillin BiologicalActivity
| Description | Pivampicillin is a penicillin antibiotic. Pivampicillin is a prodrug of Ampicillin (HY-B0522)[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Shi CK, et, al. Bactericidal composition and application thereof. CN109568323A. |
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Chemical & Physical Properties
| Density | 1.33g/cm3 |
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| Boiling Point | 679ºC at 760mmHg |
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| Molecular Formula | C22H29N3O6S |
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| Molecular Weight | 463.55 |
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| Flash Point | 364.5ºC |
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| Exact Mass | 463.17800 |
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| PSA | 153.33000 |
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| LogP | 2.35260 |
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| Index of Refraction | 1.604 |
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| InChIKey | ZEMIJUDPLILVNQ-ZXFNITATSA-N |
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| SMILES | CC(C)(C)C(=O)OCOC(=O)C1N2C(=O)C(NC(=O)C(N)c3ccccc3)C2SC1(C)C |
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| Water Solubility | Practically insoluble in water, freely soluble in methanol, soluble in anhydrous ethanol. It dissolves in dilute acids. |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- XH8380000
- CHEMICAL NAME :
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-phenylacetamido)-3,3- dimethyl-7-oxo-, hydroxymethyl ester, pivalate (ester), D-(-)-
- CAS REGISTRY NUMBER :
- 33817-20-8
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C22-H29-N3-O6-S
- MOLECULAR WEIGHT :
- 463.60
- WISWESSER LINE NOTATION :
- T45 ANV ESTJ CMVYZR& F1 F1 GVO1OVX1&1&1 &GH
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 900 mg/kg/90D-I
- TOXIC EFFECTS :
- Behavioral - muscle weakness Musculoskeletal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- PGMJAO Postgraduate Medical Journal. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1925- Volume(issue)/page/year: 68,932,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 1,310,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 148 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 1,310,1978
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Synonyms
| Pivampicillin |
| 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Pivaloyloxymethyl ampicillinate |
| Pivampicilline |
| Pondocillin |
| Pivampicilina |
| Pivampicillinum |
| Pivaloylampicillin |
| Ampicillin pivaloyloxymethyl ester |
