Introduction：Basic information about CAS 6306-71-4|N-(1H-Benzimidazol-2-yl)carbamic acid ethyl ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-(1H-Benzimidazol-2-yl)carbamic acid ethyl ester |
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| CAS Number | 6306-71-4 | Molecular Weight | 205.21 |
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| Density | 1.358 | Boiling Point | / |
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| Molecular Formula | C10H11N3O2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | ethyl N-(1H-benzimidazol-2-yl)carbamate |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Lobendazole is a potent anthelmintic. Lobendazole inhibits Giardia intestinalis strains[1]. |
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| Related Catalog | Research Areas >>Infection |
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| References | [1]. Jaime Pérez-Villanueva, et al. The giardicidal activity of lobendazole, fabomotizole, tenatoprazole and ipriflavone: A ligand-based virtual screening and in vitro study. Eur J Med Chem. 2021 Feb 5;211:113110. |
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Chemical & Physical Properties
| Density | 1.358 |
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| Molecular Formula | C10H11N3O2 |
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| Molecular Weight | 205.21 |
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| Exact Mass | 205.08500 |
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| PSA | 67.01000 |
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| LogP | 2.20430 |
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| Index of Refraction | 1.682 |
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| InChIKey | OKOVSTKGUBOSTB-UHFFFAOYSA-N |
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| SMILES | CCOC(=O)Nc1nc2ccccc2[nH]1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- EY8590000
- CHEMICAL NAME :
- Carbamic acid, (2-benzimidazolyl)-, ethyl ester
- CAS REGISTRY NUMBER :
- 6306-71-4
- LAST UPDATED :
- 199412
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C10-H11-N3-O2
- MOLECULAR WEIGHT :
- 205.24
- WISWESSER LINE NOTATION :
- T56 BM DNJ CMVO2
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04389 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 82400 ug/kg
- SEX/DURATION :
- female 8-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- ARCVBP Annales Recherches Veterinaires. (Institut National de la Recherche Agronomique, Service des Publ., Route de Saint-Cyr, 78000 Versailles, France) V.1- 1970- Volume(issue)/page/year: 21,87,1990
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 164 mg/kg
- SEX/DURATION :
- female 8-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Newborn - physical
- REFERENCE :
- ARCVBP Annales Recherches Veterinaires. (Institut National de la Recherche Agronomique, Service des Publ., Route de Saint-Cyr, 78000 Versailles, France) V.1- 1970- Volume(issue)/page/year: 21,87,1990
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Safety Information
Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Ethyl 2-benzimidazolecarbamate |
| Lobendazole |
| Ethyl 2-benzimidazolylcarbamate |
| Ethyl 1H-benzimidazol-2-ylcarbamate |
| ethyl benzimidazole-2-carbamate |
| 2-Carboethoxyaminobenzimidazole |
