CAS 63717-27-1|Amifostine Hydrate

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TE6493000

CHEMICAL NAME :

Phosphorothioic acid, S-(2-((3-aminopropyl)amino)ethyl) ester, hydrate

CAS REGISTRY NUMBER :

63717-27-1

LAST UPDATED :

199009

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C5-H15-N2-O3-P-S.H2-O

MOLECULAR WEIGHT :

232.27

WISWESSER LINE NOTATION :

Z3M2SPQQO &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

700 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,236,1969

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

375 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,911,1966