CAS 77640-21-2|p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside

Introduction:Basic information about CAS 77640-21-2|p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namep-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside
CAS Number77640-21-2Molecular Weight447.39100
Density/Boiling Point/
Molecular FormulaC18H25NO12Melting Point233-236ºC dec.
MSDS/Flash Point/

Names

Name(2R,3S,4R,5S,6S)-2-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
SynonymMore Synonyms

BiologicalActivity

Description4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. R A DiCioccio, et al. Synthesis and use of p-nitrophenyl-2-O-(alpha-L-fucopyranosyl)-beta-D-galactopyranoside for the rapid detection of substrate-specific alpha-L-fucosidases. Anal Biochem. 1981 Feb;111(1):176-83.

Chemical & Physical Properties

Melting Point233-236ºC dec.
Molecular FormulaC18H25NO12
Molecular Weight447.39100
Exact Mass447.13800
PSA204.12000
InChIKeyFMNXEBSKDAQHBI-PRQUWTJASA-N
SMILESCC1OC(OC2C(Oc3ccc([N+](=O)[O-])cc3)OC(CO)C(O)C2O)C(O)C(O)C1O

Synonyms

p-Nitrophenyl 2-O-(|A-L-fucopyranosyl)-|A-D-galactopyranoside
W0352
4-Nitrophenyl 2-O-(6-Deoxy-|A-L-galactopyranosyl)-|A-D-galactopyranoside
Fuc1-|A-2Gal-|A-PNP
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