Introduction:Basic information about CAS 77640-21-2|p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside |
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| CAS Number | 77640-21-2 | Molecular Weight | 447.39100 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H25NO12 | Melting Point | 233-236ºC dec. |
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| MSDS | / | Flash Point | / |
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Names
| Name | (2R,3S,4R,5S,6S)-2-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. R A DiCioccio, et al. Synthesis and use of p-nitrophenyl-2-O-(alpha-L-fucopyranosyl)-beta-D-galactopyranoside for the rapid detection of substrate-specific alpha-L-fucosidases. Anal Biochem. 1981 Feb;111(1):176-83. |
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Chemical & Physical Properties
| Melting Point | 233-236ºC dec. |
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| Molecular Formula | C18H25NO12 |
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| Molecular Weight | 447.39100 |
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| Exact Mass | 447.13800 |
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| PSA | 204.12000 |
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| InChIKey | FMNXEBSKDAQHBI-PRQUWTJASA-N |
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| SMILES | CC1OC(OC2C(Oc3ccc([N+](=O)[O-])cc3)OC(CO)C(O)C2O)C(O)C(O)C1O |
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Synonyms
| p-Nitrophenyl 2-O-(|A-L-fucopyranosyl)-|A-D-galactopyranoside |
| W0352 |
| 4-Nitrophenyl 2-O-(6-Deoxy-|A-L-galactopyranosyl)-|A-D-galactopyranoside |
| Fuc1-|A-2Gal-|A-PNP |