Introduction：Basic information about CAS 78439-06-2|Ceftazidime Pentahydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ceftazidime Pentahydrate |
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| CAS Number | 78439-06-2 | Molecular Weight | 546.576 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C22H32N6O12S2 | Melting Point | >150ºC(dec.) |
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| MSDS | / | Flash Point | / |
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Names
| Name | ceftazidime pentahydrate |
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| Synonym | More Synonyms |
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Ceftazidime Pentahydrate BiologicalActivity
| Description | Ceftazidime pentahydrate (GR20263 pentahydrate) is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime pentahydrate has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Richards DM, et al. Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1985 Feb;29(2):105-61. |
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Chemical & Physical Properties
| Melting Point | >150ºC(dec.) |
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| Molecular Formula | C22H32N6O12S2 |
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| Molecular Weight | 546.576 |
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| Exact Mass | 546.099121 |
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| PSA | 244.76000 |
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| LogP | -2.84 |
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| InChIKey | NMVPEQXCMGEDNH-TZVUEUGBSA-N |
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| SMILES | CC(C)(ON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CSC12)c1csc(N)n1)C(=O)[O-].O.O.O.O.O.[H+] |
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| Storage condition | 2-8°C |
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Safety Information
| Hazard Codes | Xn: Harmful; |
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| Risk Phrases | R42/43 |
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| Safety Phrases | 22-36/37-45-37-24 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 1 |
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| HS Code | 2941905990 |
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Customs
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Synonyms
| MFCD00153936 |
| EINECS 276-715-9 |
| Pyridinium, 1-[[(6R,7R)-7-[[2-(2-amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt |
| (6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl){[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| (6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl){[(2-carboxy-2-propanyl)oxy]imino}acetyl]amino}-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| Ceftazidime |
