Introduction：Basic information about CAS 827031-83-4|Verubulin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Verubulin |
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| CAS Number | 827031-83-4 | Molecular Weight | 279.336 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 398.7±38.0 °C at 760 mmHg |
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| Molecular Formula | C17H17N3O | Melting Point | 86-90 °C |
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| MSDS | / | Flash Point | 194.9±26.8 °C |
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Names
| Name | N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine |
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| Synonym | More Synonyms |
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Verubulin BiologicalActivity
| Description | Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Microtubule/TubulinSignaling Pathways >>Cytoskeleton >>Microtubule/Tubulin |
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| Target | Microtubule[1] |
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| References | [1]. Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 398.7±38.0 °C at 760 mmHg |
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| Melting Point | 86-90 °C |
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| Molecular Formula | C17H17N3O |
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| Molecular Weight | 279.336 |
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| Flash Point | 194.9±26.8 °C |
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| Exact Mass | 279.137177 |
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| PSA | 38.25000 |
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| LogP | 2.02 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.652 |
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| InChIKey | SNHCRNMVYDHVDT-UHFFFAOYSA-N |
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| SMILES | COc1ccc(N(C)c2nc(C)nc3ccccc23)cc1 |
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| Storage condition | -20°C |
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Safety Information
Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Verubulin |
| 4-Quinazolinamine, N-(4-methoxyphenyl)-N,2-dimethyl- |
| N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine |
| N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine |
