Introduction：Basic information about CAS 603-61-2|TAMARIXETIN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | TAMARIXETIN |
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| CAS Number | 603-61-2 | Molecular Weight | 316.262 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 601.8±55.0 °C at 760 mmHg |
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| Molecular Formula | C16H12O7 | Melting Point | 265-268ºC |
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| MSDS | / | Flash Point | 228.8±25.0 °C |
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Names
| Name | tamarixetin |
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| Synonym | More Synonyms |
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TAMARIXETIN BiologicalActivity
| Description | Tamarixetin (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-oxidative and anti-inflammatory effects. Tamarixetin protects against cardiac hypertrophy[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Fan C, et al. Tamarixetin protects against cardiac hypertrophy via inhibiting NFAT and AKT pathway. J Mol Histol. 2019 Aug;50(4):343-354. [2]. Park HJ, et al. Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production. J Nat Prod. 2018 Jun 22;81(6):1435-1443. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 601.8±55.0 °C at 760 mmHg |
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| Melting Point | 265-268ºC |
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| Molecular Formula | C16H12O7 |
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| Molecular Weight | 316.262 |
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| Flash Point | 228.8±25.0 °C |
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| Exact Mass | 316.058289 |
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| PSA | 120.36000 |
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| LogP | 2.42 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.741 |
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| InChIKey | FPLMIPQZHHQWHN-UHFFFAOYSA-N |
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| SMILES | COc1ccc(-c2oc3cc(O)cc(O)c3c(=O)c2O)cc1O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LK8745000
- CHEMICAL NAME :
- Flavone, 4'-methoxy-3,3',5,7-tetrahydroxy-
- CAS REGISTRY NUMBER :
- 603-61-2
- BEILSTEIN REFERENCE NO. :
- 0324993
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H12-O7
- MOLECULAR WEIGHT :
- 316.28
- WISWESSER LINE NOTATION :
- T66 BO EVJ CR CQ DO1& DQ GQ IQ
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 166 nmol/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 54,297,1978
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 22 |
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| Safety Phrases | 22-45 |
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Synonyms
| Flavone, 3,3',5,7-tetrahydroxy-4'-methoxy- |
| Quercetin 4'-methyl ether |
| Quercetin-4'-methylether |
| 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one |
| 4'-O-Methyl quercetin |
| 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)- |
| TAMARIXETIN |
| 4'-Methoxyquercetin |
| 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one |
| Flavone, 4'-methoxy-3,3',5,7-tetrahydroxy- |
| Quercetin-4'-methyl ether |
| Tamaraxetin |
| 4'-Methoxy-3,3',5,7-tetrahydroxy-flavone |
