CAS 97-90-5|Ethylene methacrylate
| Common Name | Ethylene methacrylate | ||
|---|---|---|---|
| CAS Number | 97-90-5 | Molecular Weight | 198.216 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 260.6±13.0 °C at 760 mmHg |
| Molecular Formula | C10H14O4 | Melting Point | -40 °C |
| MSDS | ChineseUSA | Flash Point | 121.8±18.2 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | ethylene glycol dimethacrylate |
|---|---|
| Synonym | More Synonyms |
Ethylene methacrylate BiologicalActivity
| Description | Ethylene glycol dimethacrylate is a methacrylate monomer, exhibits cytotoxic and genotoxic effects on human gingival fibroblasts (HGFs). Ethylene glycol dimethacrylate increases intracellular reactive oxygen species (ROS) production, causes DNA damage, increases apoptosis and causes cell cycle arrest in G1/G0 phase[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Others |
| References | [1]. Anna Bielecka-Kowalska, et al. Ethylene glycol dimethacrylate and diethylene glycol dimethacrylate exhibits cytotoxic and genotoxic effect on human gingival fibroblasts via induction of reactive oxygen species. Toxicol In Vitro. 2018 Mar:47:8-17. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 260.6±13.0 °C at 760 mmHg |
| Melting Point | -40 °C |
| Molecular Formula | C10H14O4 |
| Molecular Weight | 198.216 |
| Flash Point | 121.8±18.2 °C |
| Exact Mass | 198.089203 |
| PSA | 52.60000 |
| LogP | 2.78 |
| Vapour density | >1 (vs air) |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.449 |
| InChIKey | STVZJERGLQHEKB-UHFFFAOYSA-N |
| SMILES | C=C(C)C(=O)OCCOC(=O)C(=C)C |
| Stability | Unstable - may polymerize upon exposure to light. Incompatible with strong acids, strong oxidizing agents, strong bases. |
| Water Solubility | soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 5820 umol/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,264,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3204 No. of Facilities: 983 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 6295 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3204 No. of Facilities: 562 (estimated) No. of Industries: 8 No. of Occupations: 14 No. of Employees: 9073 (estimated) No. of Female Employees: 3604 (estimated)
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 5820 umol/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,264,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3204 No. of Facilities: 983 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 6295 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3204 No. of Facilities: 562 (estimated) No. of Industries: 8 No. of Occupations: 14 No. of Employees: 9073 (estimated) No. of Female Employees: 3604 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H335 |
| Precautionary Statements | P280-P304 + P340 + P312-P333 + P313 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R37;R43 |
| Safety Phrases | S24-S37 |
| RIDADR | UN3334 9 |
| WGK Germany | 1 |
| RTECS | OZ4400000 |
| Hazard Class | 9.0 |
| HS Code | 2916140000 |
Customs
| HS Code | 2916190090 |
|---|---|
| Summary | 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0% |
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Synonyms
| Ethylene methacrylate |
| Ethylene dimethacrylate |
| Glycol dimethacrylate |
| Ethane-1,2-diyl bis(2-methylprop-2-enoate) |
| 1UY1&VO2OVY1&U1 |
| MFCD00008590 |
| 2-Propenoic acid, 2-methyl-, 1,2-ethanediyl ester |
| Ethyldiol methacrylate |
| Ethane-1,2-diyl bis(2-methylacrylate) |
| EINECS 202-617-2 |
| 1,2-Ethanediyl bis(2-methylacrylate) |
| Methacrylic acid ethylene ester |
| 1,2-Ethanediol dimethacrylate |
| Ethylene glycol dimethacrylate |
