CAS 98886-44-3|Fosthiazate

Introduction：Basic information about CAS 98886-44-3|Fosthiazate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Fosthiazate BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Synonyms

Common Name	Fosthiazate
CAS Number	98886-44-3	Molecular Weight	283.348
Density	1.3±0.1 g/cm3	Boiling Point	371.3±25.0 °C at 760 mmHg
Molecular Formula	C₉H₁₈NO₃PS₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	178.3±23.2 °C
Symbol	GHS05, GHS06, GHS09	Signal Word	Danger

Names

Name	fosthiazate
Synonym	More Synonyms

Fosthiazate BiologicalActivity

Description	Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Neuronal Signaling >>AChE
References	[1]. Lianshan Liet al. Chiral organophosphorous pesticide fosthiazate: absolute configuration, stereoselective bioactivity, toxicity, and degradation in vegetables. J Agric Food Chem. 2020 Jul 22;68(29):7609-7616.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	371.3±25.0 °C at 760 mmHg
Molecular Formula	C₉H₁₈NO₃PS₂
Molecular Weight	283.348
Flash Point	178.3±23.2 °C
Exact Mass	283.046570
PSA	107.02000
LogP	0.94
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.541
InChIKey	DUFVKSUJRWYZQP-UHFFFAOYSA-N
SMILES	CCOP(=O)(SC(C)CC)N1CCSC1=O
Storage condition	0-6°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TB1707000

CHEMICAL NAME :: Phosphonothioic acid, (2-oxo-3-thiazolidinyl)-, O-ethyl S-(1-methylpropyl) ester

CAS REGISTRY NUMBER :: 98886-44-3

LAST UPDATED :: 199506

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H18-N-O3-P-S2

MOLECULAR WEIGHT :: 283.37

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 57 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AGJAEP Agrochemcicals Japan. (Japan Plant Protection Association, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.62- 1993- Volume(issue)/page/year: (65),13,1994

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 558 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AGJAEP Agrochemcicals Japan. (Japan Plant Protection Association, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.62- 1993- Volume(issue)/page/year: (65),13,1994

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 861 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AGJAEP Agrochemcicals Japan. (Japan Plant Protection Association, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.62- 1993- Volume(issue)/page/year: (65),13,1994

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 91 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AGJAEP Agrochemcicals Japan. (Japan Plant Protection Association, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.62- 1993- Volume(issue)/page/year: (65),13,1994

Safety Information

Symbol	GHS05, GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301 + H311 + H331-H317-H318-H410
Supplemental HS	Toxic by eye contact.
Precautionary Statements	Missing Phrase - N15.00950417-P280-P302 + P352 + P312-P304 + P340 + P312-P305 + P351 + P338 + P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases	R21;R23/25;R39;R41;R43;R50/53
Safety Phrases	S53-S25-S26-S39-S45-S60-S61
RIDADR	UN 2810
RTECS	TB1707000
Packaging Group	III
Hazard Class	6.1(b)

Synonyms

O-Ethyl S-(1-methylpropyl) (2-oxo-3-thiazolidinyl)phosphonothioate

O-ethyl S-(1-methylpropyl) P-(2-oxo-3-thiazolidinyl)phosphonothioate

Fosthiazate

Phosphonothioic acid, (2-oxo-3-thiazolidinyl)-, O-ethyl S-(1-methylpropyl) ester

S-sec-Butyl O-ethyl 2-oxo-3-thiazolidinylphosphonothioate

Fosthiazate [ISO:BSI]

IKI 1145

O-Ethyl S-(1-methylpropyl) (2-oxo-1,3-thiazolidin-3-yl)phosphonothioate

MFCD00274595

T5NVSTJ APO2&S1Y2&1

(3RS)-3-[(RS)-sec-butylthio(ethoxy)phosphinoyl]-1,3-thiazolidin-2-one

(RS)-[S-(RS)-sec-butyl O-ethyl 2-oxo-1,3-thiazolidin-3-ylphosphonothioate]

3-[butan-2-ylsulfanyl(ethoxy)phosphoryl]-1,3-thiazolidin-2-one

O-Ethyl S-(butan-2-yl) (2-oxo-1,3-thiazolidin-3-yl)phosphonothioate

S-butan-2-yl O-ethyl (2-oxo-1,3-thiazolidin-3-yl)phosphonothioate

(RS)-S-sec-butyl-O-ethyl-2-oxo-1,3-thiazolidin-3-ylphosphonothioate

S-sec-Butyl O-ethyl (2-oxo-1,3-thiazolidin-3-yl)phosphonothioate

Phosphonothioic acid, P-(2-oxo-3-thiazolidinyl)-, O-ethyl S-(1-methylpropyl) ester

Nemathorin

S-sec-Butyl O-ethyl (2-oxo-1,3-thiazolidine-3-yl)phosphonothioate

(Ξ)-[S-(2Ξ)-butan-2-yl O-ethyl (2-oxo-1,3-thiazolidin-3-yl)phosphonothioate]

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