CAS 3312-60-5|N1-Cyclohexylpropane-1,3-diamine
| Common Name | N1-Cyclohexylpropane-1,3-diamine | ||
|---|---|---|---|
| CAS Number | 3312-60-5 | Molecular Weight | 156.268 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 238.7±8.0 °C at 760 mmHg |
| Molecular Formula | C9H20N2 | Melting Point | −17-−15 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 112.3±22.0 °C |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | N'-cyclohexylpropane-1,3-diamine |
|---|---|
| Synonym | More Synonyms |
N1-Cyclohexylpropane-1,3-diamine BiologicalActivity
| Description | N-(3-Aminopropyl)cyclohexylamine, a cyclohexylamine derivative, acts as a selective and competitive inhibitor of spermidine synthase. N-(3-Aminopropyl)cyclohexylamine can be used for the research of neurological diseases[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| References | [1]. P J Chu, et al.Antagonistic effect of N-(3-Aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons. Jpn J Pharmacol. 1995 Dec;69(4):311-5. |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 238.7±8.0 °C at 760 mmHg |
| Melting Point | −17-−15 °C(lit.) |
| Molecular Formula | C9H20N2 |
| Molecular Weight | 156.268 |
| Flash Point | 112.3±22.0 °C |
| Exact Mass | 156.162643 |
| PSA | 38.05000 |
| LogP | 1.27 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.484 |
| InChIKey | ITZPOSYADVYECJ-UHFFFAOYSA-N |
| SMILES | NCCCNC1CCCCC1 |
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C: Corrosive; |
| Risk Phrases | R34 |
| Safety Phrases | S26-S27-S28-S36/37/39-S45 |
| RIDADR | UN 2735 8/PG 2 |
| WGK Germany | 1 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2921300090 |
Customs
| HS Code | 2921300090 |
|---|---|
| Summary | 2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
Articles8
More Articles| Effects of inhibitors of spermidine synthase and spermine synthase on polyamine synthesis in rat tissues. Biochem. Pharmacol. 45(9) , 1897-903, (1993) Several inhibitors of aminopropyltransferases, developed recently in this laboratory, were tested for their specificity by measuring their effects on six enzyme activities related to polyamine biosynt... | |
| Specific depletion of spermidine and spermine in HTC cells treated with inhibitors of aminopropyltransferases. J. Biochem. 117(2) , 339-45, (1995) The effects of a potent spermidine synthase inhibitor, trans-4-methylcyclohexylamine (4MCHA), and a spermine synthase inhibitor, N-(3-aminopropyl)cyclohexylamine (APCHA), on polyamine biosynthesis and... | |
| Inhibition of cell growth by combination of alpha-difluoromethylornithine and an inhibitor of spermine synthase. J. Biochem. 117(4) , 824-9, (1995) The inhibitory effect on cell growth of a combination of alpha-difluoromethylornithine (DFMO) and an inhibitor of aminopropyl transferase was examined. N-(3-aminopropyl)cyclohexylamine (APCHA) and tra... |
Synonyms
| N1-Cyclohexylpropane-1,3-diamine |
| MFCD00003838 |
| N-Cyclohexylpropane-1,3-diamine |
| EINECS 222-001-7 |
| 3-amino-1-cyclohexylaminopropane |
| N-Cyclohexyl-1,3-diaminopropane |
| 1-(Cyclohexylamino)-3-aminopropane |
| N-Cyclohexyltrimethylendiamin |
| 3-(Aminopropyl)cyclohexylamine |
| 3-(Cyclohexylamino)-1-propylamine |
| 1,3-Propanediamine, N-cyclohexyl- |
| 3-Cyclohexylaminopropylamine |
| N-Cyclohexyl-1,3-propanediamine |
| Cyclohexylamine, N-(3-aminopropyl)- |
| N-(3-Aminopropyl)cyclohexylamine |
| N-Cyclohexylpropylene 1,3-diamine |
| 3-Cyclohexylamino-1-propylamine |
| Cyclohexyl-1,3-propanediamine |
| N-Cyclohexyl-1,3-propylenediamine |
| 3-Cyclohexylaminopropylamin |
