CAS 3237-44-3|2-HYDROXY-2-ISOPROPYLSUCCINIC ACID

Introduction：Basic information about CAS 3237-44-3|2-HYDROXY-2-ISOPROPYLSUCCINIC ACID, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 2-HYDROXY-2-ISOPROPYLSUCCINIC ACID BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles26
7. Synonyms

Common Name	2-HYDROXY-2-ISOPROPYLSUCCINIC ACID
CAS Number	3237-44-3	Molecular Weight	176.16700
Density	1.342g/cm3	Boiling Point	306.4ºC at 760mmHg
Molecular Formula	C₇H₁₂O₅	Melting Point	144-146ºC(lit.)
MSDS	ChineseUSA	Flash Point	153.3ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	2-isopropylmalic acid
Synonym	More Synonyms

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID BiologicalActivity

Description	α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	α-Isopropylmalate (500 μM) increases LEU3 protein (Leu3p)-dependent transcription[1]. α-Isopropylmalate (10 mM, 48 h) increases reporter gene expression in preadipocytes (30A5)[2].

Chemical & Physical Properties

Density	1.342g/cm3
Boiling Point	306.4ºC at 760mmHg
Melting Point	144-146ºC(lit.)
Molecular Formula	C₇H₁₂O₅
Molecular Weight	176.16700
Flash Point	153.3ºC
Exact Mass	176.06800
PSA	94.83000
InChIKey	BITYXLXUCSKTJS-UHFFFAOYSA-N
SMILES	CC(C)C(O)(CC(=O)O)C(=O)O

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-37/39
RIDADR	NONH for all modes of transport
HS Code	2918199090

Customs

HS Code	2918199090
Summary	2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles26

Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes.

Metabolomics 11 , 1277-1286, (2015)

Biomarkers for the development of type 2 diabetes (T2D) are useful for prediction and intervention of the disease at earlier stages. In this study, we performed a longitudinal study of changes in meta...

Human metabolic responses to chronic environmental polycyclic aromatic hydrocarbon exposure by a metabolomic approach.

J. Proteome Res. 14 , 2583-93, (2015)

The toxicities of polycyclic aromatic hydrocarbons (PAHs) have been extensively explored due to their carcinogenic and mutagenic potency; however, little is known about the metabolic responses to chro...

A potential tool for diagnosis of male infertility: Plasma metabolomics based on GC-MS.

Talanta 147 , 82-9, (2015)

Male infertility has become an important public health problem worldwide. Nowadays the diagnosis of male infertility frequently depends on the results of semen quality or requires more invasive surgic...

Synonyms

2-hydroxy-2-isopropyl-succinic acid

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID

2-Hydroxy-2-isopropyl-bernsteinsaeure

MFCD00075003

2-Hydroxy-2-isopropylbutanedioic acid

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