CAS 18525-25-2|Serotonin hydrogen maleate

Introduction：Basic information about CAS 18525-25-2|Serotonin hydrogen maleate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles180
7. Synonyms

Common Name	Serotonin hydrogen maleate
CAS Number	18525-25-2	Molecular Weight	292.28700
Density	/	Boiling Point	416.1ºC at 760mmHg
Molecular Formula	C₁₄H₁₆N₂O₅	Melting Point	154-158ºC (dec.)
MSDS	ChineseUSA	Flash Point	205.4ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	Serotonin hydrogen maleate
Synonym	More Synonyms

Chemical & Physical Properties

Boiling Point	416.1ºC at 760mmHg
Melting Point	154-158ºC (dec.)
Molecular Formula	C₁₄H₁₆N₂O₅
Molecular Weight	292.28700
Flash Point	205.4ºC
Exact Mass	292.10600
PSA	136.64000
LogP	1.78680
Vapour Pressure	1.63E-07mmHg at 25°C
InChIKey	LTEXAUVYLLADEB-BTJKTKAUSA-N
SMILES	NCCc1c[nH]c2ccc(O)cc12.O=C(O)C=CC(=O)O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NM2560000

CHEMICAL NAME :: Indol-5-ol, 3-(2-aminoethyl)-, maleate

CAS REGISTRY NUMBER :: 18525-25-2

LAST UPDATED :: 198212

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H12-N2-O.C4-H4-O4

MOLECULAR WEIGHT :: 292.32

WISWESSER LINE NOTATION :: T56 BMJ D2Z GQ &QV1U1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 158 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - hypermotility, diarrhea

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 33,282,1970

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	22
RIDADR	NONH for all modes of transport
RTECS	NM2560000
HS Code	2933990090

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles180

Nest building is impaired in the Ts65Dn mouse model of Down syndrome and rescued by blocking 5HT2a receptors.

Neurobiol. Learn. Mem. 116 , 162-71, (2014)

Down syndrome (DS) has an incidence of about 1/700 births, and is therefore the most common cause of cognitive and behavioral impairments in children. Recent studies on mouse models of DS indicate tha...

Permeation of Dopamine Sulfate through the Blood-Brain Barrier.

PLoS ONE 10 , e0133904, (2015)

Dopamine sulfate (DA-3- and DA-4-S) have been determined in the human brain, but it is unclear whether they are locally formed in the central nervous system (CNS), or transported into the CNS from per...

Kinetics of serotonin oxidation by heme-Aβ relevant to Alzheimer's disease.

J. Biol. Inorg. Chem. 19(8) , 1355-65, (2014)

Serotonin (5-HT) is an essential neurotransmitter for cognitive functions and formation of new memories. A deficit in 5-HT dependent neuronal activity is somewhat specific for Alzheimer's disease. Met...

Synonyms

5-HYDROXYTRYPTAMINE MALEATE SALT

MFCD00043256

EINECS 242-399-6

3-(2-Aminoethyl)-5-hydroxyindole hydrogen maleate,5-HT,5-Hydroxytryptamine hydrogen maleate

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