CAS 32222-00-7|(Tyr8)-Bradykinin

Introduction：Basic information about CAS 32222-00-7|(Tyr8)-Bradykinin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. (Tyr8)-Bradykinin BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	(Tyr8)-Bradykinin
CAS Number	32222-00-7	Molecular Weight	1076.21000
Density	/	Boiling Point	/
Molecular Formula	C₅₀H₇₃N₁₅O₁₂	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	arg-pro-pro-gly-phe-ser-pro-tyr-arg
Synonym	More Synonyms

(Tyr8)-Bradykinin BiologicalActivity

Description	[Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard[1].
Related Catalog	Research Areas >>Cardiovascular DiseaseResearch Areas >>EndocrinologySignaling Pathways >>MAPK/ERK Pathway >>ERKSignaling Pathways >>GPCR/G Protein >>Bradykinin ReceptorSignaling Pathways >>Stem Cell/Wnt >>ERK
Target	Bradykinin B2 Receptor (B2R) ERK1 ERK2
In Vitro	[Tyr8] Bradykinin (10 nM, 2 min) produces a rapid increase in phosphorylated ERK1/2[1]. Western Blot Analysis[1] Cell Line: Serum-deprived trabecular meshwork cells Concentration: 10 nM Incubation Time: 2 min Result: Produced a rapid increase in phosphorylated ERK1/2 that was equivalent in magnitude to that observed for Bradykinin (HY-P0206).

Chemical & Physical Properties

Molecular Formula	C₅₀H₇₃N₁₅O₁₂
Molecular Weight	1076.21000
Exact Mass	1075.56000
PSA	434.01000
LogP	0.98690
InChIKey	MWVUEDATXZGOMI-UHFFFAOYSA-N
SMILES	NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)N1CCCC1C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCN=C(N)N)C(=O)O

Synonyms

BRADYKININ (TYR8)

Asp-Pro-Pro-Gly-Phe-Ser-Pro-Tyr-Arg

L-Arg-L-Pro-L-Pro-Gly-L-Phe-L-Ser-L-Pro-L-Tyr-L-Arg-OH

tyrosine8-bradykinin

Tyr8-bradykinin

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