Introduction：Basic information about CAS 34118-92-8|N-AcetylprocainaMide hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-AcetylprocainaMide hydrochloride |
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| CAS Number | 34118-92-8 | Molecular Weight | 313.82 |
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| Density | / | Boiling Point | 500ºC at 760mmHg |
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| Molecular Formula | C15H24ClN3O2 | Melting Point | 184-186ºC(lit.) |
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| MSDS | USA | Flash Point | 256.2ºC |
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Names
| Name | 4-acetamido-N-[2-(diethylamino)ethyl]benzamide,hydrochloride |
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| Synonym | More Synonyms |
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N-AcetylprocainaMide hydrochloride BiologicalActivity
| Description | N-Acetylprocainamide (Acecainide) hydrochloride is a class III antiarrhythmic, which blocks K+ channels[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel |
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| References | [1]. Nakahara T, et al. Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle. Eur J Pharmacol. 2001 Mar 9;415(1):73-8. |
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Chemical & Physical Properties
| Boiling Point | 500ºC at 760mmHg |
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| Melting Point | 184-186ºC(lit.) |
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| Molecular Formula | C15H24ClN3O2 |
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| Molecular Weight | 313.82 |
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| Flash Point | 256.2ºC |
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| Exact Mass | 313.15600 |
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| PSA | 61.44000 |
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| LogP | 2.98250 |
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| Appearance of Characters | powder |
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| InChIKey | IYEWBJUCJHKLHD-UHFFFAOYSA-N |
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| SMILES | CCN(CC)CCNC(=O)c1ccc(NC(C)=O)cc1.Cl |
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| Storage condition | −20°C |
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| Water Solubility | H2O: 50 mg/mL |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S24/25 |
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| RIDADR | UN 3249 |
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| WGK Germany | 3 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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| HS Code | 2924299090 |
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Customs
| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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| Drug-herb interaction: effect of St John's wort on bioavailability and metabolism of procainamide in mice. Arch. Pathol. Lab. Med. 131(7) , 1094-8, (2007) St John's wort induces the activity of the cytochrome P450 enzyme system causing treatment failure because of increased metabolism of many drugs. Procainamide is metabolized by a different pathway to ... | |
Synonyms
| NAPA |
| Acecainide hydrochloride |
| EINECS 251-831-2 |
| MFCD00012501 |
| Acecainide HCl |
| N-ACETYLPROCAINAMIDE HYDROCHLORIDE |
| ASL-601 |
