Introduction：Basic information about CAS 64206-54-8|valerylsalicylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | valerylsalicylic acid |
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| CAS Number | 64206-54-8 | Molecular Weight | 222.24 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 357.6±25.0 °C at 760 mmHg |
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| Molecular Formula | C12H14O4 | Melting Point | 86-87ºC(lit.) |
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| MSDS | USA | Flash Point | 135.5±16.7 °C |
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Names
| Name | valerylsalicylic acid |
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| Synonym | More Synonyms |
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valerylsalicylic acid BiologicalActivity
| Description | Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COX |
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| Target | COX-1 |
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| References | [1]. Siqueira-Junior JM, et al. Effects of valeryl salicylate, a COX-1 inhibitor, on models of acute inflammation in mice. Pharmacol Res. 2003 Nov;48(5):437-43. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 357.6±25.0 °C at 760 mmHg |
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| Melting Point | 86-87ºC(lit.) |
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| Molecular Formula | C12H14O4 |
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| Molecular Weight | 222.24 |
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| Flash Point | 135.5±16.7 °C |
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| Exact Mass | 222.089203 |
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| PSA | 63.60000 |
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| LogP | 2.78 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.530 |
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| InChIKey | WJHZBTMHUNVIKC-UHFFFAOYSA-N |
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| SMILES | CCCCC(=O)Oc1ccccc1C(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VO6840000
- CHEMICAL NAME :
- Salicylic acid, valerate
- CAS REGISTRY NUMBER :
- 64206-54-8
- BEILSTEIN REFERENCE NO. :
- 3292055
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C12-H14-O4
- MOLECULAR WEIGHT :
- 222.26
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Behavioral - analgesia
- REFERENCE :
- JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 2,229,1979
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S22-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2918990090 |
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Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| valerylsalicylic acid |
| 2-Valeryloxybenzoic acid Valerylsalicylic acid vsa |
| 2-pentanoyloxybenzoic acid |
| Benzoic acid, 2-[(1-oxopentyl)oxy]- |
| 2-(Pentanoyloxy)benzoic acid |
| MFCD00041466 |
