CAS 79-69-6|irone

CHEMICAL IDENTIFICATION

RTECS NUMBER :

EN0335000

CHEMICAL NAME :

3-Buten-2-one, 4-(2,5,6,6-tetramethyl-2-cyclohexen-1-yl)-

CAS REGISTRY NUMBER :

79-69-6

LAST UPDATED :

199709

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C14-H22-O

MOLECULAR WEIGHT :

206.36

WISWESSER LINE NOTATION :

L6UTJ A1 D1 E1 E1 F1U1V1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1950 mg/kg/8W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :

CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 33,3069,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5036 No. of Facilities: 85 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 4041 (estimated) No. of Female Employees: 276 (estimated)

Food Chem. Toxicol. 45 Suppl 1 , S272-5, (2007)

A toxicologic and dermatologic review of alpha-irone when used as a fragrance ingredient is presented.