Introduction：Basic information about CAS 81069-02-5|DTSSP Crosslinker, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DTSSP Crosslinker |
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| CAS Number | 81069-02-5 | Molecular Weight | 564.54200 |
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| Density | 1.94 | Boiling Point | / |
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| Molecular Formula | C14H16N2O14S4 | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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Names
| Name | 3,3'-Dithiobis(sulfosuccinimidylpropionate) |
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| Synonym | More Synonyms |
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DTSSP Crosslinker BiologicalActivity
| Description | DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
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| References | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |
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Chemical & Physical Properties
| Density | 1.94 |
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| Molecular Formula | C14H16N2O14S4 |
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| Molecular Weight | 564.54200 |
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| Exact Mass | 563.94800 |
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| PSA | 303.46000 |
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| LogP | 0.13240 |
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| Index of Refraction | 1.693 |
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| InChIKey | VOTJUWBJENROFB-UHFFFAOYSA-N |
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| SMILES | O=C(CCSSCCC(=O)ON1C(=O)CC(S(=O)(=O)O)C1=O)ON1C(=O)CC(S(=O)(=O)O)C1=O |
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Safety Information
| Hazard Codes | Xi |
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| Safety Phrases | 26-36 |
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Synonyms
| N,N'-dioctyl-3,3'-disulfanediyl-bis-propionamide |
| N,N'-Bis-n-octyl-3,3'-dithiopropionamide |
| 3,3'-disulfanediylbis(N-octylpropanamide) |
| 3,3-dithiobis(sulfosuccinimidyl propionate) |
| N,N'-di-n-octyl-3,3'-dithiodipropionamide |
| N,N'-Di-n-octyl-3,3'-dithiodipropionamid |
| Propanamide,3,3'-dithiobis[N-octyl |
| (SCH2CH2CONHC8H17)2 |
| 3,3'-dithiobis(N-octylpropionamide) |
