Introduction：Basic information about CAS 58336-35-9|LD 490, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | LD 490 |
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| CAS Number | 58336-35-9 | Molecular Weight | 241.28500 |
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| Density | 1.32g/cm3 | Boiling Point | 486.3ºC at 760 mmHg |
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| Molecular Formula | C15H15NO2 | Melting Point | 130 °C |
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| MSDS | / | Flash Point | 201ºC |
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Names
| Name | Coumarin 6H |
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| Synonym | More Synonyms |
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LD 490 BiologicalActivity
| Description | Coumarin 6H, a Coumarin (Coumarin (HY-N0709)) derivative, is a laser dye. The fluorescence emission of Coumarin 6H can be enhanced by hydrogen bonding interactions[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | 具有扭曲嵌段和更强供电子久洛利定基团的 Coumarin 6H 在被荧光猝灭基团抑制时表现出更高的量子产率、更好的生物相容性以及更少的背景荧光。因此，探针 LH-1 中的 Coumarin 6H 可能有助于降低背景荧光。在探针LH-1中，Coumarin 6H 荧光团的荧光不仅可以被 N-N 基团的旋转猝灭，还可以通过供体激发光诱导电子转移 (d-PET) 机制被 2,4-二硝基苯基团猝灭[2]。 |
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| References | [1]. P M French, et al. Passively mode-locked cw Coumarin 6 ring dye laser. Opt Lett. 1989 Feb 15;14(4):217-8. [2]. Zhixiang Han, et al. A novel fluorescent probe with extremely low background fluorescence for sensing hypochlorite in zebrafish. Anal Biochem. 2020 Aug 1;602:113795. |
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Chemical & Physical Properties
| Density | 1.32g/cm3 |
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| Boiling Point | 486.3ºC at 760 mmHg |
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| Melting Point | 130 °C |
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| Molecular Formula | C15H15NO2 |
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| Molecular Weight | 241.28500 |
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| Flash Point | 201ºC |
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| Exact Mass | 241.11000 |
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| PSA | 33.45000 |
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| LogP | 2.55680 |
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| Index of Refraction | 1.665 |
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| InChIKey | MZSOXGPKUOAXNY-UHFFFAOYSA-N |
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| SMILES | O=c1ccc2cc3c4c(c2o1)CCCN4CCC3 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DJ3310000
- CHEMICAL NAME :
- 1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizin-11-one, 2,3,6,7-tetrahydro-
- CAS REGISTRY NUMBER :
- 58336-35-9
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C15-H15-N-O2
- MOLECULAR WEIGHT :
- 241.31
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 100 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7,511,1985
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Synonyms
| C 6H |
| 2,3,6,7-tetrahydro-1H,5H-quinolizino<9,9a,1-gh>coumarin |
| 2,3,6,7-tetrahydro-1H,5H,11H-benzopyrano<6,7,8-i,j>quinolizin-11-one |
| Exciton LD 490 |
| 2,3,5,6-1H,4H-tetrahydroquinolizino[9,9a,1-gh]coumarin |
| MFCD00227485 |
| coumarin-6H |
| 2,3,6,7-Tetrahydro-1H,5H,11H-(1)benzopyrano(6,7,8-ij)-quinolizin-11-one |
| EINECS 261-213-4 |
| LD 490 |
| 2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one |
| 2,3,5,6-Tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one |
