Introduction：Basic information about CAS 52334-81-3|2-Chloro-5-(trifluoromethyl)pyridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Chloro-5-(trifluoromethyl)pyridine |
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| CAS Number | 52334-81-3 | Molecular Weight | 181.543 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 171.6±35.0 °C at 760 mmHg |
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| Molecular Formula | C6H3ClF3N | Melting Point | 32-34 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 57.6±25.9 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 2-Chloro-5-trifluoromethylpyridine |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 171.6±35.0 °C at 760 mmHg |
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| Melting Point | 32-34 °C(lit.) |
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| Molecular Formula | C6H3ClF3N |
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| Molecular Weight | 181.543 |
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| Flash Point | 57.6±25.9 °C |
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| Exact Mass | 180.990616 |
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| PSA | 12.89000 |
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| LogP | 2.44 |
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| Vapour Pressure | 1.8±0.3 mmHg at 25°C |
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| Index of Refraction | 1.447 |
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| InChIKey | JFZJMSDDOOAOIV-UHFFFAOYSA-N |
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| SMILES | FC(F)(F)c1ccc(Cl)nc1 |
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| Storage condition | 0-6°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- US7530000
- CHEMICAL NAME :
- Pyridine, 2-chloro-5-(trifluoromethyl)-
- CAS REGISTRY NUMBER :
- 52334-81-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C6-H3-Cl-F3-N
- MOLECULAR WEIGHT :
- 181.55
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4 gm/m3/6H/4W-I
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5500 mg/kg/21D-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
MUTATION DATA - TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 800 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 301,57,1993
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xn:Harmful |
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| Risk Phrases | R20/21/22;R36/37/38 |
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| Safety Phrases | S26-S37/39-S36/37/39 |
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| RIDADR | 2811 |
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| WGK Germany | 3 |
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| RTECS | US7530000 |
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| Packaging Group | III |
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| Hazard Class | 6.1 |
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| HS Code | 2933399090 |
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Customs
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles1
More Articles
| Three chloro (trifluoromethyl) pyridines as model substrates for regioexhaustive functionalization.Cottet F and Schlosser M. European J. Org. Chem. 18 , 3793-98, (2004)
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Synonyms
| 2-Chloro-5-Trifluoromethylpyridine |
| EINECS 257-856-5 |
| Pyridine, 2-chloro-5-(trifluoromethyl)- |
| 2-Chloro-5-(trifluoromethyl)pyridine |
| T6NJ BG EXFFF |
| MFCD00042225 |
