CAS 330-95-0|Nicarbazin
| Common Name | Nicarbazin | ||
|---|---|---|---|
| CAS Number | 330-95-0 | Molecular Weight | 426.383 |
| Density | 1.4663 (rough estimate) | Boiling Point | 414.8ºC at 760 mmHg |
| Molecular Formula | C19H18N6O6 | Melting Point | 265-275ºC |
| MSDS | ChineseUSA | Flash Point | 204.7ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 1,3-bis(4-nitrophenyl)urea,4,6-dimethyl-1H-pyrimidin-2-one |
|---|---|
| Synonym | More Synonyms |
Nicarbazin BiologicalActivity
| Description | Nicarbazin is an effective anticoccidial agent for chickens[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
| In Vivo | Nicarbazin does not adversely affect the development of immunity or resistance to re-infection with E. acervulina oocysts[1]. |
| References | [1]. Ott, W. H., et al. Biological Studies on Nicarbazin, a New Anticoccidial Agent. Poultry Science. 1956. 35(6), 1355–1367. [2]. CUCKLER AC, et al. The effect of nicarbazin on the development of immunity to avian coccidia. J Parasitol. 1956 Dec;42(6):593-607. |
Chemical & Physical Properties
| Density | 1.4663 (rough estimate) |
|---|---|
| Boiling Point | 414.8ºC at 760 mmHg |
| Melting Point | 265-275ºC |
| Molecular Formula | C19H18N6O6 |
| Molecular Weight | 426.383 |
| Flash Point | 204.7ºC |
| Exact Mass | 426.128784 |
| PSA | 178.78000 |
| LogP | 5.13840 |
| Index of Refraction | 1.6000 (estimate) |
| InChIKey | UKHWDRMMMYWSFL-UHFFFAOYSA-N |
| SMILES | Cc1cc(C)[nH]c(=O)n1.O=C(Nc1ccc([N+](=O)[O-])cc1)Nc1ccc([N+](=O)[O-])cc1 |
| Storage condition | 0-6°C |
| Water Solubility | DMSO: soluble0.5mg/mL |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | FE0900000 |
| HS Code | 2933990090 |
Customs
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles27
More Articles| Veterinary drug residues in domestic and imported foods of animal origin in the Republic of Korea. Food. Addit. Contam. Part. B. Surveill. 8 , 106-12, (2015) The Korean National Residue Programme comprises three different approaches for evaluating domestic and imported foods of animal origin: monitoring, surveillance/enforcement and an exploratory test pro... | |
| Sensitivity of Eimeria field isolates in the United States: responses of nicarbazin-containing anticoccidials. Poult. Sci. 87(9) , 1760-7, (2008) A series of studies were conducted to assess the drug sensitivity of 26 coccidial field isolates to the anticoccidial effects of nicarbazin (NIC) and narasin + NIC (NAR + NIC). Isolates were collected... | |
| Evaluation of nicarbazin as a potential waterfowl contraceptive using mallards as a model. Poult. Sci. 85(7) , 1275-84, (2006) Contraception may provide a useful nonlethal management tool to reduce wild bird populations. We tested the efficacy of nicarbazin (NCZ) as a contraceptive for waterfowl and assessed health effects of... |
Synonyms
| EINECS 206-359-1 |
| Nirazin |
| Nicarbazine |
| Nicrazin |
| Nicarbazin |
| Nicarb |
| Nicrazine |
| Nicoxin |
| Nicarbasin |
| N,N'-bis(4-Nitrophenyl)urea compound with 4,6-dimethyl-2-pyrimidinone |
| MK 75 |
