Introduction：Basic information about CAS 503610-43-3|Rosuvastatin Lactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Rosuvastatin Lactone |
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| CAS Number | 503610-43-3 | Molecular Weight | 463.522 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 695.0±65.0 °C at 760 mmHg |
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| Molecular Formula | C22H26FN3O5S | Melting Point | 131℃ |
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| MSDS | / | Flash Point | 374.1±34.3 °C |
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Names
| Name | Rosuvastatin Lactone |
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| Synonym | More Synonyms |
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Rosuvastatin Lactone BiologicalActivity
| Description | Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A) (HMG-CoA inhibitor)[1]. |
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| Related Catalog | Research Areas >>Metabolic Disease |
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| References | [1]. Lee HB, et al. Occurrence and fate of rosuvastatin, rosuvastatin lactone, and atorvastatin in Canadian sewage and surface water samples. Chemosphere. 2009 Nov;77(10):1285-91. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 695.0±65.0 °C at 760 mmHg |
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| Melting Point | 131℃ |
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| Molecular Formula | C22H26FN3O5S |
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| Molecular Weight | 463.522 |
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| Flash Point | 374.1±34.3 °C |
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| Exact Mass | 463.157715 |
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| PSA | 118.07000 |
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| LogP | 0.42 |
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| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
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| Index of Refraction | 1.615 |
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| InChIKey | SOEGVMSNJOCVHT-VEUZHWNKSA-N |
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| SMILES | CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1C=CC1CC(O)CC(=O)O1 |
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| Storage condition | -20℃ |
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Synonyms
| Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-5-[(E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl- |
| RosuvastatinLactone |
| (3R,5R)-ROSUVASTATIN LACTONE |
| Rosuvastatin lactone |
| N-[4-(4-Fluorophenyl)-5-{(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]vinyl}-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide |
| ROSUVASTATIN-5S-LACTONE |
