CAS 475473-26-8|CORM-3

Introduction:Basic information about CAS 475473-26-8|CORM-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCORM-3
CAS Number475473-26-8Molecular Weight296.62800
Density/Boiling Point/
Molecular FormulaC5H4ClNO5RuMelting Point/
MSDSUSAFlash Point/

Names

NameRuthenium, tricarbonylchloro(gl​ycinato-​κN,​κO)​-​, (OC-​6-​44)​
SynonymMore Synonyms

CORM-3 BiologicalActivity

DescriptionCORM-3, a water-soluble carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels[1][2][3].
Related CatalogResearch Areas >>Inflammation/Immunology
References

[1]. Foresti R, et al. Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule. Br J Pharmacol. 2004 Jun;142(3):453-60.

[2]. Lee DW, et al. Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages. Biochem Biophys Res Commun. 2017 Nov 18;493(2):957-963.

[3]. Huang Y, et al. Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-κB signaling in lens epithelial cells. Exp Eye Res. 2018 Jan;166:29-39.

Chemical & Physical Properties

Molecular FormulaC5H4ClNO5Ru
Molecular Weight296.62800
Exact Mass296.89800
PSA112.85000
Storage condition-20℃

Safety Information

Hazard CodesN
RIDADRNONH for all modes of transport

Synonyms

MFCD07364048
CAS 1627676-59-8|PFI-2
CAS 1246529-32-7|MPI-0479605
Recommended......
TOP