Introduction：Basic information about CAS 7720-39-0|2-Aminoimidazole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Aminoimidazole |
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| CAS Number | 7720-39-0 | Molecular Weight | 83.092 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 313.1±25.0 °C at 760 mmHg |
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| Molecular Formula | C3H5N3 | Melting Point | / |
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| MSDS | / | Flash Point | 168.9±10.4 °C |
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Names
| Name | 1H-Imidazol-2-amine |
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| Synonym | More Synonyms |
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2-Aminoimidazole BiologicalActivity
| Description | 2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM[1][2][3]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Immunology/Inflammation >>ArginaseSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | bacteria[1] Ki: 3.6 mM (human arginase I)[3] |
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| References | [1]. Thompson RJ, et, al. Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-Aminoimidazole-based antibiofilm agent. Biochemistry. 2012 Dec 11;51(49):9776-8. [2]. Jacobs L, et, al. 2-Aminoimidazoles as potent inhibitors of contaminating brewery biofilms. Biofouling. 2021 Feb 11;1-17. [3]. Ilies M, et, al. 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J Med Chem. 2010 May 27;53(10):4266-76. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 313.1±25.0 °C at 760 mmHg |
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| Molecular Formula | C3H5N3 |
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| Molecular Weight | 83.092 |
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| Flash Point | 168.9±10.4 °C |
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| Exact Mass | 83.048347 |
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| PSA | 54.70000 |
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| LogP | -0.59 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.648 |
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| InChIKey | DEPDDPLQZYCHOH-UHFFFAOYSA-N |
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| SMILES | Nc1ncc[nH]1 |
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 36/37/38 |
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| Safety Phrases | 26-37/39 |
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| HS Code | 2933290090 |
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Customs
| HS Code | 2933290090 |
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| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| N-imidazolylamine |
| EINECS 231-751-4 |
| 1H-Imidazol-2-amine |
| MFCD00792530 |
| 2-aminoimidazole |
