CAS 2391-03-9|Dexbrompheniramine Maleate

Introduction：Basic information about CAS 2391-03-9|Dexbrompheniramine Maleate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Synonyms

Common Name	Dexbrompheniramine Maleate
CAS Number	2391-03-9	Molecular Weight	435.31200
Density	/	Boiling Point	403ºC at 760mmHg
Molecular Formula	C₂₀H₂₃BrN₂O₄	Melting Point	/
MSDS	/	Flash Point	197.5ºC

Names

Name	dexbrompheniramine maleate
Synonym	More Synonyms

Chemical & Physical Properties

Boiling Point	403ºC at 760mmHg
Molecular Formula	C₂₀H₂₃BrN₂O₄
Molecular Weight	435.31200
Flash Point	197.5ºC
Exact Mass	434.08400
PSA	90.73000
LogP	3.63950
Vapour Pressure	1.05E-06mmHg at 25°C
InChIKey	SRGKFVAASLQVBO-DASCVMRKSA-N
SMILES	CN(C)CCC(c1ccc(Br)cc1)c1ccccn1.O=C(O)C=CC(=O)O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US4026200

CAS REGISTRY NUMBER :: 2391-03-9

LAST UPDATED :: 198910

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C16-H19-Br-N2.C4-H4-O4

MOLECULAR WEIGHT :: 435.36

WISWESSER LINE NOTATION :: T6NJ BYR DE&2N1&1 &QV1U1VQ -+

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 191 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 104 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 176 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 106 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 259 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961

Safety Information

Hazard Codes	T: Toxic;
Risk Phrases	25
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	US4026200

Synonyms

Dexbrompheniramine maleate salt

(3S)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine,(Z)-but-2-enedioic acid

(+)-Brompheniramine maleate salt

(S)-Brompheniramine Maleate

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