CAS 347840-03-3|N,N-Dimethylglycine-d6 hydrochloride

Introduction:Basic information about CAS 347840-03-3|N,N-Dimethylglycine-d6 hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN,N-Dimethylglycine-d6 hydrochloride
CAS Number347840-03-3Molecular Weight145.62
Density/Boiling Point190-192ºC(lit.)
Molecular FormulaC4H4D6ClNO2Melting Point/
MSDSChineseUSAFlash Point/
Symbol
GHS07
Signal WordWarning

Names

Name2-[bis(trideuteriomethyl)amino]acetic acid,hydrochloride
SynonymMore Synonyms

N,N-Dimethylglycine-d6 hydrochloride BiologicalActivity

DescriptionN,N-Dimethylglycine-d6 hydrochloride is the deuterium labeled N,N-Dimethylglycine[1].
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

Boiling Point190-192ºC(lit.)
Molecular FormulaC4H4D6ClNO2
Molecular Weight145.62
Exact Mass145.07800
PSA40.54000
LogP0.43460
InChIKeyFKASAVXZZLJTNX-TXHXQZCNSA-N
SMILESCN(C)CC(=O)O.Cl

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319
Precautionary StatementsP305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk Phrases36/38
Safety Phrases26-36/37
RIDADRNONH for all modes of transport

Synonyms

N,N-Dimethyl-d6-glycine hydrochloride
N-Methylsarcosine-dimethyl-d6 hydrochloride
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