CAS 525-64-4|2,7-Diaminofluorene

Introduction：Basic information about CAS 525-64-4|2,7-Diaminofluorene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles12
7. Synonyms

Common Name	2,7-Diaminofluorene
CAS Number	525-64-4	Molecular Weight	196.248
Density	1.3±0.1 g/cm3	Boiling Point	467.0±38.0 °C at 760 mmHg
Molecular Formula	C₁₃H₁₂N₂	Melting Point	160-162 °C(lit.)
MSDS	ChineseUSA	Flash Point	283.6±26.3 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	2,7-Diaminofluorene
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	467.0±38.0 °C at 760 mmHg
Melting Point	160-162 °C(lit.)
Molecular Formula	C₁₃H₁₂N₂
Molecular Weight	196.248
Flash Point	283.6±26.3 °C
Exact Mass	196.100052
PSA	52.04000
LogP	1.60
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.750
InChIKey	SNCJAJRILVFXAE-UHFFFAOYSA-N
SMILES	Nc1ccc2c(c1)Cc1cc(N)ccc1-2

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LL6980000

CHEMICAL NAME :: Fluorene-2,7-diamine

CAS REGISTRY NUMBER :: 525-64-4

LAST UPDATED :: 199709

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C13-H12-N2

MOLECULAR WEIGHT :: 196.27

WISWESSER LINE NOTATION :: L B656 HHJ EZ KZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1000 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3600 mg/kg/27D-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: DNA repair

TYPE OF TEST :: Mutation test systems - not otherwise specified

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Kidney

DOSE/DURATION :: 80 ug/L

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5160 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 16 (estimated) No. of Female Employees: 16 (estimated)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	LL6980000
HS Code	2921590090

Customs

HS Code	2921590090
Summary	2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles12

Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test.

Mutat. Res. 290(2) , 175-82, (1993)

Drosophila melanogaster stock consisting of meiotic recombination deficient (Rec-) double mutant mei-9a mei-41D5 males and Rec+ females was exposed at the larval stage to an aromatic amine or a polycy...

[An interesting peroxidase staining.--utilization of blended substrate of mixed 2, 7-FDA and Laurent's acid-- (author's transl)].

Rinsho Byori. 29(6) , 613-6, (1981)

Sensitive assay systems for detection of hemoglobin with 2,7-diaminofluorene: histochemistry and colorimetry for erythrodifferentiation.

Anal. Biochem. 149 , 117, (1985)

Sensitive and rapid assays, colorimetry and histochemistry, for hemoglobin in erythroid cells are established. The assays are based on pseudoperoxidase activity of hemoglobin using 2,7-diaminofluorene...

Synonyms

2,7-diamine-9H-fluorene

Diaminofluorene

2,7-FLUORENEDIAMINE

7-amino-9H-fluoren-2-ylamine

MFCD00001128

DAF

2,5-DIMETHYL-4-METHOXYBENZENEBORONIC ACID

2,7-Diaminofluorene

9H-Fluorene-2,7-diamine

EINECS 208-377-5

fluorene-2,7-diyldiamine

2,7-DiaMinoflyorene

fluorene-2,7-diamine

9H-Fluorene-2,7-diamine (9CI)

2,7-diamino-9H-fluorene

2,7-DIAMINO-FLUOROENE

Recommended......