CAS 716-61-0|(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
Introduction：Basic information about CAS 716-61-0|(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol | ||
|---|---|---|---|
| CAS Number | 716-61-0 | Molecular Weight | 212.203 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 451.9±45.0 °C at 760 mmHg |
| Molecular Formula | C9H12N2O4 | Melting Point | 163-165ºC |
| MSDS | ChineseUSA | Flash Point | 227.1±28.7 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 451.9±45.0 °C at 760 mmHg |
| Melting Point | 163-165ºC |
| Molecular Formula | C9H12N2O4 |
| Molecular Weight | 212.203 |
| Flash Point | 227.1±28.7 °C |
| Exact Mass | 212.079712 |
| PSA | 112.30000 |
| LogP | 0.13 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.630 |
| InChIKey | OCYJXSUPZMNXEN-RKDXNWHRSA-N |
| SMILES | NC(CO)C(O)c1ccc([N+](=O)[O-])cc1 |
| Storage condition | −20°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 2 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,207,1994
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 2 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,207,1994
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | UN 3259 |
| WGK Germany | 3 |
| RTECS | TY3100000 |
Articles5
More Articles| [Studies on the resolution of racemic gossypol. IV. Use of threo (-) or (+)-1-(p-nitrophenyl)-1,3-dihydroxypropylamine-2 as the resolving agent]. Yao Xue Xue Bao 25(6) , 430-4, (1990) Threo (-) or (+)-1-(p-nitrophenyl)-1,3-dihydroxypropylamine-2 was found to be a useful resolving agent for racemic gossypol. The optical and chemical stability of the condensate of enantiomeric gossyp... | |
| Investigation of Batten disease with the yeast Saccharomyces cerevisiae. Mol. Genet. Metab. 66(4) , 314-9, (1999) The CLN3 gene, which encodes the protein whose absence is responsible for Batten disease, the most common inherited neurovisceral storage disease of childhood, was identified in 1995. The function of ... | |
| High-performance liquid chromatographic determination of chloramphenicol and 2-amino-1-(p-nitrophenyl)-1,3-propanediol in pharmaceutical formulations. J. Chromatogr. A. 170(1) , 282-7, (1979) |
Synonyms
| 2-Amino-1-(4-nitrophenyl)-1,3-propanediol |
| 2-amino-1-(4-nitrophenyl)propane-1,3-diol |
| D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol |
| (1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol |
| D-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol |
| 1,3-Propanediol, 2-amino-1-(4-nitrophenyl)- |
| D-threo-(-)-2-Amino-1-(p-nitrophenyl)-1,3-propanediol |
| D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL |
| 1-(p-nitrophenyl)-2-amino-1,3-propanediol |
| MFCD00078126 |
| 1,3-Propanediol, 2-amino-1- (p-nitrophenyl)- |
| 1,3-Propanediol, 2-amino-1- (4-nitrophenyl)- |
| 1,3-Propanediol, 2-amino-1-(p-nitrophenyl)-, D-threo-(-)- |
| EINECS 211-938-7 |
