CAS 18016-80-3|S-(-)-LISURIDE

Introduction：Basic information about CAS 18016-80-3|S-(-)-LISURIDE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. S-(-)-LISURIDE BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	S-(-)-LISURIDE
CAS Number	18016-80-3	Molecular Weight	456.53500
Density	1.23g/cm3	Boiling Point	603.4ºC at 760mmHg
Molecular Formula	C₂₄H₃₂N₄O₅	Melting Point	/
MSDS	/	Flash Point	318.7ºC

Names

Name	lisuride
Synonym	More Synonyms

S-(-)-LISURIDE BiologicalActivity

Description	Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels[1][2].
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Dopamine ReceptorSignaling Pathways >>Neuronal Signaling >>Dopamine ReceptorResearch Areas >>Neurological Disease
Target	D2 Receptor
In Vivo	lisuride (30~100 μg/kg) decreases the rate of dopa formation[2].
References	[1]. Rinne UK. Lisuride, a dopamine agonist in the treatment of early Parkinson's disease. Neurology. 1989;39(3):336-339. [2]. Kehr W. Effect of lisuride and other ergot derivatives on monoaminergic mechanisms in rat brain. Eur J Pharmacol. 1977;41(3):261-273.

Chemical & Physical Properties

Density	1.23g/cm3
Boiling Point	603.4ºC at 760mmHg
Molecular Formula	C₂₄H₃₂N₄O₅
Molecular Weight	456.53500
Flash Point	318.7ºC
Exact Mass	456.23700
PSA	125.97000
LogP	2.97230
Vapour Pressure	1.9E-15mmHg at 25°C
Index of Refraction	1.659
InChIKey	BKRGVLQUQGGVSM-KBXCAEBGSA-N
SMILES	CCN(CC)C(=O)NC1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1

Synonyms

Lisurida

LISURIDE

3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea

Methylergol Carbamide

Lisuridum

Lysuride

Lysurid

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