CAS 18968-99-5|MAGNESIUM PEMOLINE

Introduction：Basic information about CAS 18968-99-5|MAGNESIUM PEMOLINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	MAGNESIUM PEMOLINE
CAS Number	18968-99-5	Molecular Weight	234.49200
Density	/	Boiling Point	313.6ºC at 760 mmHg
Molecular Formula	C₉H₁₀MgN₂O₄	Melting Point	/
MSDS	/	Flash Point	143.4ºC

Names

Name	magnesium,2-amino-5-phenyl-1,3-oxazol-4-one,dihydroxide
Synonym	More Synonyms

Chemical & Physical Properties

Boiling Point	313.6ºC at 760 mmHg
Molecular Formula	C₉H₁₀MgN₂O₄
Molecular Weight	234.49200
Flash Point	143.4ºC
Exact Mass	234.04900
PSA	105.14000
LogP	0.38150
InChIKey	JOPOQPCBCUIPFX-UHFFFAOYSA-L
SMILES	NC1=NC(=O)C(c2ccccc2)O1.[Mg+2].[OH-].[OH-]

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RY1105000

CHEMICAL NAME :: Pemoline magnesium

CAS REGISTRY NUMBER :: 18968-99-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C9-H10-Mg-N2-O4

MOLECULAR WEIGHT :: 234.52

WISWESSER LINE NOTATION :: T5OYMV EHJ BUM ER &-MG-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 149 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Gastrointestinal - nausea or vomiting

REFERENCE :: CPEDAM Clinical Pediatrics (Philadelphia). (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1962- Volume(issue)/page/year: 18,761,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 485 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,810,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - irritability Lungs, Thorax, or Respiration - other changes

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 181,441,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 487 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 181,441,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - changes in motor activity (specific assay) Skin and Appendages - hair

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 181,441,1969

Synonyms

Pemoline magnesium chelate

2-Amino-5-phenyl-2-oxazolin-4-one + Mg(OH)2

Magnesium pemoline

Pemoline magnesium

Pemoline magnesium hydroxide mixture

Tamilan

Pemoline magnesium hydroxide

Pemolin and magnesium hydroxide

DEA No. 1530

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